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Diet, Lifestyle and Chronic Disease in Early Life—2nd Edition

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Pediatric Nutrition".

Deadline for manuscript submissions: 15 July 2025 | Viewed by 818

Special Issue Editors


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Guest Editor
Department of Maternal and Child Health, School of Public Health, Peking University, Beijing 100191, China
Interests: child growth and development; obesity; epidemiology; environmental factors associated with maternal and child health
Special Issues, Collections and Topics in MDPI journals
Department of Maternal and Child Health, School of Public Health, Peking University, Beijing 100191, China
Interests: early life exposures; NDDs; HDP
Special Issues, Collections and Topics in MDPI journals
Department of Maternal and Child Health, School of Public Health, Peking University, Beijing 100191, China
Interests: micronutrients; pregnancy; infant
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

We are excited to announce our upcoming Special Issue on “Diet, Lifestyle and Chronic Disease in Early Life—2nd Edition”. This Special Issue will focus on the associations of nutrition and lifestyle factors with the development of chronic diseases later in early life.

We welcome original research articles, systemic reviews and meta-analyses that explore the following topics:

  • The effects of early-life nutritional and metabolic status on childhood health outcomes related to chronic diseases;
  • The associations of diet and lifestyle factors on chronic disease risk during childhood and adolescence;
  • Strategies to improve early-life nutrition and lifestyle to prevent chronic diseases.

We encourage submissions from a variety of disciplines, including nutrition, epidemiology, public health, and medicine. Manuscripts will undergo a rigorous peer-review process to ensure their high quality and relevance to this Special Issue’s theme.

We look forward to receiving your contributions.

Sincerely,

Prof. Dr. Haijun Wang
Dr. Yuelong Ji
Dr. Hui Wang
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nutrients is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • early-life nutrition
  • chronic disease
  • obesity
  • mental health
  • early-life origin
  • children nutrition

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Published Papers (1 paper)

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Research

14 pages, 5772 KiB  
Article
Maternal Glycemia and Its Pattern Associated with Offspring Neurobehavioral Development: A Chinese Birth Cohort Study
by Zhichao Yuan, Tao Su, Li Yang, Lei Xi, Hai-Jun Wang and Yuelong Ji
Nutrients 2025, 17(2), 257; https://doi.org/10.3390/nu17020257 - 11 Jan 2025
Viewed by 676
Abstract
Background/Objectives: This study investigates the impact of maternal glycemic levels during early and late pregnancy on offspring neurodevelopment in China. Methods: Fasting plasma glucose (FPG) and triglyceride (TG) levels were measured in maternal blood during pregnancy, and the TyG index was calculated to [...] Read more.
Background/Objectives: This study investigates the impact of maternal glycemic levels during early and late pregnancy on offspring neurodevelopment in China. Methods: Fasting plasma glucose (FPG) and triglyceride (TG) levels were measured in maternal blood during pregnancy, and the TyG index was calculated to assess insulin resistance. Hyperglycemia was defined as FPG > 5.1 mmol/L. Neurodevelopmental outcomes in offspring aged 6–36 months were evaluated using the China Developmental Scale for Children, focusing on developmental delay (DD) and developmental quotient (DQ). Mothers were categorized into four glycemic groups: healthy glycemia group (HGG), early pregnancy hyperglycemia group (EHG), late pregnancy hyperglycemia group (LHG), and full-term hyperglycemia group (FHG). Linear and logistic regression models were applied. Results: Among 1888 mother–child pairs, hyperglycemia and FPG were associated with an increased risk of overall DD (aOR = 1.68; 95% CI 1.07–2.64) and lower DQ (aBeta = −1.53; 95% CI −2.70 to −0.36). Elevated FPG was linked to DD in fine motor and social behaviors. Compared to HGG, LHG and FHG significantly increased the risk of overall DD (aOR = 2.18; 95% CI 1.26–3.77; aOR = 2.64; 95% CI 1.38–5.05), whereas EHG did not. Male offspring were particularly vulnerable to early pregnancy hyperglycemia (aBeta = −2.80; 95% CI −4.36 to −1.34; aOR = 2.05; 95% CI 1.10–3.80). Conclusions: Maternal glycemic levels during pregnancy influence offspring neurodevelopment, with persistent hyperglycemia significantly increasing DD risk. Early pregnancy hyperglycemia particularly affects male offspring, underscoring the need for glycemic management during pregnancy. Full article
(This article belongs to the Special Issue Diet, Lifestyle and Chronic Disease in Early Life—2nd Edition)
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