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Nutritional Epidemiology of Cancer

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Nutritional Epidemiology".

Deadline for manuscript submissions: 25 November 2025 | Viewed by 535

Special Issue Editors

Dr. Nerea Becerra-Tomás

E-Mail Website
Guest Editor
Nutrition and Mental Health (NUTRISAM) Research Group, Universitat Rovira i Virgili, 43201 Reus, Spain
Interests: nutritional epidemiology; Mediterranean diet; nuts; legumes; cancer; diabetes; cardiovascular disease; systematic review; meta-analysis
Dr. Magdalena Stepien

E-Mail Website
Guest Editor
Joint Research Centre, European Commission, Via E. Fermi, 2749, I-21027 Ispra, VA, Italy
Interests: nutrition; epidemiology; cancer

Special Issue Information

Dear Colleagues,

We are pleased to announce the launch of a new Special Issue of Nutrients entitled the “Nutritional Epidemiology of Cancer”.

Cancer is a major public health problem worldwide, with 20 million new cases and 9.7 million cancer-related deaths recorded in 2022, according to the latest GLOBOCAN estimates. It is worth noting that most types of cancer can be prevented by adopting a healthy lifestyle. In this context, the influence of nutrition on the prevention and management of cancer is undeniable. Nevertheless, when it comes to dietary recommendations, the scientific evidence of the impact of nutrition on cancer development has been judged to be convincingly causal or protective for only a limited number of nutrients or food groups. Hence, this Special Issue seeks to further clarify the association between nutrition and cancer in order to provide high-quality evidence that can be used as a basis for developing dietary recommendations for cancer prevention.

All studies (cohort studies, case–control studies, Mendelian randomization studies, randomized trials, reviews, meta-analyses, and umbrella reviews) focusing on the role of diet (food groups, dietary patterns, nutrients, dietary components) in the development of cancer are welcome.

Dr. Nerea Becerra-Tomás
Dr. Magdalena Stepien
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nutrients is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • diet
  • nutrition
  • bioactive compounds
  • phytochemicals
  • cancer prevention

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Published Papers (1 paper)

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Review

16 pages, 614 KiB  
Review
The Impact of Dietary Intake of Furocoumarins and Furocoumarin-Rich Foods on the Risk of Cutaneous Melanoma: A Systematic Review
by Isabelle Kaiser, Anja Rappl, Lena S. Bolay, Annette B. Pfahlberg, Markus V. Heppt and Olaf Gefeller
Nutrients 2025, 17(8), 1296; https://doi.org/10.3390/nu17081296 - 8 Apr 2025
Viewed by 229
Abstract
Background/Objectives: Furocoumarins, chemical compounds found in many plant species, have a photosensitizing effect on the skin when applied topically and, by interacting with ultraviolet radiation (UVR), stimulate melanoma cells to proliferate. Whether dietary intake of furocoumarins acts as a melanoma risk factor has [...] Read more.
Background/Objectives: Furocoumarins, chemical compounds found in many plant species, have a photosensitizing effect on the skin when applied topically and, by interacting with ultraviolet radiation (UVR), stimulate melanoma cells to proliferate. Whether dietary intake of furocoumarins acts as a melanoma risk factor has been investigated in several epidemiological studies, which are synthesized in our systematic review. Methods: The study protocol was registered with PROSPERO (registration number: CRD42023428596). We conducted an in-depth literature search in three databases coupled with forward and backward citation tracking and expert consultations to identify all epidemiological studies, irrespective of their design, addressing the association between a furocoumarin-containing diet and melanoma risk. We extracted information on the study details and results in a standardized manner and evaluated the risk of bias of the results using the Joanna Briggs Institute’s critical appraisal tools. Results: We identified 20 publications based on 19 different studies providing information on the association between dietary furocoumarin intake and melanoma risk. We refrained from a meta-analytical synthesis of the results because of the large heterogeneity in exposure assessment, operationalization of furocoumarin intake in the analyses, and analytical methods of the studies. In a qualitative synthesis, we found moderate evidence supporting the notion that dietary furocoumarin intake at higher levels acts as a risk factor for cutaneous melanoma. Conclusions: Our systematic review provides an overview of the current epidemiological evidence, but it could not clearly answer whether and to what extent dietary furocoumarin intake increases melanoma risk. Future epidemiological analyses focusing on this topic require more comprehensive dietary and UVR exposure data to better characterize the individual total furocoumarin intake and its interplay with UVR exposure patterns. Full article
(This article belongs to the Special Issue Nutritional Epidemiology of Cancer)
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