The Impact of Gut Microbiota and Their Metabolites on Chronic Diseases
A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Prebiotics and Probiotics".
Deadline for manuscript submissions: 25 September 2025 | Viewed by 806
Special Issue Editors
Interests: microbiota; microbiome; immune system; intestine; bioactive compounds; food; nutrition; inflammation; food allergy
Interests: in vivo experiments; nutrition; oxidative stress; inflammation; obesity; liver disorders; gut-microbiota-derived metabolites; metabolic disorders; interaction between the gut and liver
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The gut microbiota and their metabolites play a crucial role in maintaining an individual’s overall health. Imbalances in the gut environment and composition of the microbiota have been linked to the onset and progression of various chronic diseases, including metabolic, autoimmune, and neurological disorders. Factors such as genetics, environment, lifestyle, and age significantly contribute to these imbalances.
Recent research has increasingly highlighted the importance of gut microbiota in the context of chronic diseases. Maintaining a proper balance of microbial strains and preserving biodiversity in the gut are essential for preventing both local and systemic inflammation. Additionally, the gut-brain axis—a bidirectional communication network between the gut and the brain—underscores the connection between microbiota and mental health conditions, including depression and anxiety. In autoimmune diseases such as rheumatoid arthritis and multiple sclerosis, the gut microbiota can influence immune responses, either mitigating or exacerbating symptoms.
With this Special Issue, we invite contributions from various disciplines to enhance our understanding in this rapidly evolving field. Insights into the complex interplay between gut microbiota and chronic diseases could lead to innovative therapeutic approaches and preventive strategies. Submissions of original research articles and literature reviews concerning the complex interplay between gut microbiota and chronic diseases are encouraged.
Dr. Joanna Fotschki
Dr. Bartosz Fotschki
Guest Editors
Manuscript Submission Information
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Keywords
- gut microbiota
- dysbiosis
- intestinal bacteria
- chronic diseases
- gut–brain axis
- probiotics
- prebiotics
- psychobiotics
- symbiotic
- postbiotics
- parabiotics
- metabolic disorders
- autoimmune disorders
- immune response
- dietary interventions
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