The Impact of Gut Microbiota and Their Metabolites on Chronic Diseases

Dear Colleagues,

The gut microbiota and their metabolites play a crucial role in maintaining an individual’s overall health. Imbalances in the gut environment and composition of the microbiota have been linked to the onset and progression of various chronic diseases, including metabolic, autoimmune, and neurological disorders. Factors such as genetics, environment, lifestyle, and age significantly contribute to these imbalances.

Recent research has increasingly highlighted the importance of gut microbiota in the context of chronic diseases. Maintaining a proper balance of microbial strains and preserving biodiversity in the gut are essential for preventing both local and systemic inflammation. Additionally, the gut-brain axis—a bidirectional communication network between the gut and the brain—underscores the connection between microbiota and mental health conditions, including depression and anxiety. In autoimmune diseases such as rheumatoid arthritis and multiple sclerosis, the gut microbiota can influence immune responses, either mitigating or exacerbating symptoms.

With this Special Issue, we invite contributions from various disciplines to enhance our understanding in this rapidly evolving field. Insights into the complex interplay between gut microbiota and chronic diseases could lead to innovative therapeutic approaches and preventive strategies. Submissions of original research articles and literature reviews concerning the complex interplay between gut microbiota and chronic diseases are encouraged.

Dr. Joanna Fotschki
Dr. Bartosz Fotschki
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nutrients is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.