Microbiome, Metabolites, and Allergic Diseases

Dear Colleagues,

We are pleased to announce a Special Issue dedicated to exploring the intricate relationships between the microbiome, metabolites, and allergic diseases. As the prevalence of allergic conditions continues to rise globally, understanding the underlying mechanisms and potential interventions becomes increasingly critical. This Special Issue will gather cutting-edge research and review articles that provide novel insights into how the microbiome and its metabolites influence the development, progression, and management of allergic diseases.

Scope and Themes

The human microbiome, comprising trillions of microorganisms residing in the gut, skin, and other body sites, plays a crucial role in maintaining health. Emerging evidence suggests that the microbiome’s composition and the metabolites it produces are intimately linked to the immune system’s function and may significantly influence the pathogenesis of allergic diseases such as asthma, allergic rhinitis, atopic dermatitis, and food allergies.

We invite submissions that address, but are not limited to, the following topics:

• Diet, Nutrition, and the Microbiome in Allergy Prevention and Treatment: Articles exploring how diet and nutrition influence the microbiome and its metabolites, as well as how these factors can be leveraged for the prevention and management of allergic diseases;
• Microbiome Composition and Allergic Diseases: Studies that elucidate the differences in microbiome profiles between individuals with and without allergic diseases, as well as how these differences may predispose people to or protect them against allergic conditions;
• Microbial Metabolites as Modulators of Immune Function: Research focused on how specific metabolites produced by the microbiome, such as short-chain fatty acids (SCFAs), bile acids, and others, interact with the immune system to modulate allergic responses;
• Probiotics, Prebiotics, and Synbiotics in Allergy Management: Investigations into the therapeutic potential of probiotics, prebiotics, and synbiotics for altering the microbiome to treat or prevent allergic diseases;
• Mechanistic Studies Linking the Microbiome to Allergic Inflammation: Experimental studies that provide mechanistic insights into how the microbiome and its metabolites contribute to the initiation and perpetuation of allergic inflammation;
• Clinical Trials and Interventions Targeting the Microbiome in Allergic Diseases: Reports on clinical trials that assess the efficacy of microbiome-targeted interventions, including fecal microbiota transplantation, dietary modifications, and the use of microbial-derived therapies in allergic diseases;

Submission Guidelines

Manuscripts should be submitted online via the Nutrients website by 2024/12/31. All submissions will undergo a rigorous peer-review process. Accepted papers will be published in this Special Issue and widely disseminated to the scientific community.

For more details on the submission guidelines, please visit the Nutrients submission page. We encourage authors from diverse disciplines, including immunology, microbiology, nutrition, and clinical medicine, to contribute to this exciting and rapidly evolving field.

I look forward to receiving your valuable contributions to this Special Issue.

Prof. Dr. I-Jen Wang
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nutrients is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• diet
• nutrition
• microbiome composition
• allergic diseases
• immune function