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Vitamin/Mineral Intake and Dietary Quality in Relation to Cancer Risk

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Micronutrients and Human Health".

Deadline for manuscript submissions: 15 September 2025 | Viewed by 1139

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School of Public Health and Health Systems, University of Waterloo, Waterloo, ON N2L 3G1, Canada
Interests: public health; nutritional epidemiology; grounded theory; theoretical biology
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Dietary intake in relation to cancer and comorbid chronic conditions like diabetes, chronic kidney disease, obesity, metabolic syndrome, and bone mineral disorders is emerging as an important public health risk factor for cancer incidence and prevention. Vitamins and minerals, including vitamins A, D, E, K, C, the B vitamins, calcium, phosphorus, iron, magnesium, copper, selenium, etc., are essential dietary factors related to the quality of dietary intake. These essential dietary factors may also have important relationships with cancer risk through nutrient deficiencies and nutrient overload. Any studies and reviews that find correlations of specific vitamin/mineral intakes with cancer risk and comorbid conditions will be considered for publication in this Special Issue. Additionally, studies and reviews will be considered if they examine the role of vitamin/mineral intake in the quality of dietary patterns associated with cancer risk and comorbidities, such as the Mediterranean diet, ketogenic diet, high-protein diet, low-fat diet, plant-based diet, calorie restriction, fasting-mimicking diet, intermittent fasting, ultra-processed food, whole food, and organic food.

Dr. Ronald B. Brown
Guest Editor

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Keywords

  • vitamins and minerals
  • cancer risk
  • dietary quality
  • nutrient deficiency and overload
  • dietary patterns
  • Mediterranean diet
  • ketogenic diet
  • high-protein diet
  • low-fat diet
  • plant-based diet
  • calorie restriction
  • fasting-mimicking diet
  • intermittent fasting
  • ultra-processed food
  • whole and organic food

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Published Papers (1 paper)

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12 pages, 940 KB  
Systematic Review
Zinc Status and Occurrence of Thyroid Cancer: Systematic Review and Meta-Analysis
by Aline Alves Soares, Yasmin Guerreiro Nagashima, Grasiela Piuvezam, Camila Xavier Alves, Kleyton Santos de Medeiros, Márcia Marília Gomes Dantas Lopes and Jose Brandao-Neto
Nutrients 2025, 17(17), 2820; https://doi.org/10.3390/nu17172820 - 29 Aug 2025
Viewed by 910
Abstract
Background and Objective: Thyroid cancer (TC) represents the most common group of endocrine tumors, and its incidence has increased over the last four decades. The imbalance of trace elements, such as zinc (Zn), has been investigated due to the thyroid’s sensitivity to [...] Read more.
Background and Objective: Thyroid cancer (TC) represents the most common group of endocrine tumors, and its incidence has increased over the last four decades. The imbalance of trace elements, such as zinc (Zn), has been investigated due to the thyroid’s sensitivity to these elements. Zn is essential for thyroid hormone action and may be involved in the pathogenesis of TC. This systematic review and meta-analysis aim to contribute to the discussion on the association between low serum Zn concentrations and the occurrence of TC. Materials and Methods: The search was carried out in the PubMed/MEDLINE, Scopus, Embase, LILACS and Web of Science databases, including observational studies published until December 2024. The primary outcome was low serum Zn concentration and the occurrence of TC. Three independent reviewers selected the studies and extracted the data from the original publications. The risk of bias was assessed using the Newcastle–Ottawa Quality Assessment Scale. Data analysis was performed using R software (V.4.3.1), and heterogeneity was calculated using the I2 statistic, with results based on random effects models. Results: A total of 10 studies (n = 7 case–control and n = 3 cross-sectional) with sample sizes ranging from 44 to 294 individuals were included. The results indicated that serum Zn levels were not significantly lower in patients with TC compared with healthy controls (mean difference: −251.77; 95% confidence interval: −699.09, 195.54; I2 = 100%, very low certainty). Conclusions: Further investigations, including rigorously designed observational studies with representative samples and improved control of potential confounding variables are indispensable. Full article
(This article belongs to the Special Issue Vitamin/Mineral Intake and Dietary Quality in Relation to Cancer Risk)
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