Micronutrients and Autoimmune Diseases
A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Micronutrients and Human Health".
Deadline for manuscript submissions: closed (30 September 2023) | Viewed by 12292
Special Issue Editor
Interests: rheumatic diseases; autoimmune and autoinflammatory diseases; spondyloarthritis; rheumatoid arthritis; dietary interventions in rheumatological diseases
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Micronutrients are vitamins and minerals that have an important role in the body’s health, since they are involved in the production of enzymes, hormones, and other substances essential for normal growth and body development. Indeed, micronutrients play an important role in immunomodulatory processes through their interactions with both innate and adaptative immunity, as well as by influencing the pro-/anti-inflammatory cytokine balance. Micronutrient serum levels depend on multiple factors, such as nutrition, the gut microbiome, age, inflammation, and gender. Gender differences also affect the colon luminal environment, which is in turn dependent on the status of B vitamins. Among pathological conditions it is possible to list the following: anemia related to lower iron, folic acid, and vitamin B12 (B12) levels; reduced bone mineral density, mainly related to low calcium and 25(OH) D); a high risk of a pro-thrombotic state, linked to folic acid and B12; and chronic bowel inflammation, in which folic acid, calcium, and 25(OH)D play a key role in the pathogenesis. A deficiency in micronutrients has been documented to be common among patients with autoimmune disorders, associated with a heightened inflammatory status and comorbidities. In this Special Issue we aim to evaluate the relationship between micronutrients and autoimmunity in the pathogenesis of, clinical patterns of, and therapeutical approaches to autoimmune diseases.
Dr. Maria Sole Chimenti
Guest Editor
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Keywords
- micronutrients
- autoimmunity
- autoimmune diseases
- vitamin
- minerals
- metabolism
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