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Endocrine Dyscrasia and Nutritional Regulation

A special issue of Nutrients (ISSN 2072-6643).

Deadline for manuscript submissions: closed (30 September 2019) | Viewed by 12340

Special Issue Editor


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Guest Editor
Department of Pharmaceutical Sciences (DISFARM), University of Milan, via Balzaretti 9, 20133 Milan, Italy
Interests: estrogens; estrogen receptors; liver; metabolism; diet; sex differences; female; reproduction; fertility status; women ageing
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Special Issue Information

Dear Colleagues,

Endocrine signals influence the regulation of nutrition and, conversely, macronutrients—carbohydrates, proteins, and lipids—report to the endocrine system about the availability of nutrients. This strict interplay between the endocrine system and nutrients has been preserved and perfected during evolution to adapt the metabolic response to environments that did not guarantee a constant nutritional supply. This regulation reached its maximum degree of complexity in female mammals, to ensure the survival of the mother and the fetus.

Excessive or unbalanced dietary intake, over-exposure to endocrine disrupting molecules, physiological aging (particularly in women), and, generally, endocrine alterations can impair such interplay, promoting obesity and obesity-associated diseases.

This Special Issue welcomes original research articles and literature reviews concerning the interplay between endocrine signaling and nutrients under physio-pathological conditions, with a particular focus on:

- The description of mechanisms of action, pathways, and targets at the molecular level, including the gut microbiota
- The role of individual nutrients or specific foods in the development, prevention, and treatment of endocrine-related chronic conditions
- The role of sexual hormones and the correlation between endocrine signaling, nutrition, and fertility
- The consequences of aging

Dr. Sara Della Torre
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nutrients is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Nutrients
  • Endocrine signals
  • Endocrine-related diseases
  • Endocrine disrupting nutrients
  • Microbiota
  • Fertility
  • Sexual dimorphism
  • Aging

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Published Papers (1 paper)

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Review

32 pages, 2102 KiB  
Review
The Gut Microbiota Affects Host Pathophysiology as an Endocrine Organ: A Focus on Cardiovascular Disease
by Marco Busnelli, Stefano Manzini and Giulia Chiesa
Nutrients 2020, 12(1), 79; https://doi.org/10.3390/nu12010079 - 27 Dec 2019
Cited by 57 | Viewed by 11504
Abstract
It is widely recognized that the microorganisms inhabiting our gastrointestinal tract—the gut microbiota—deeply affect the pathophysiology of the host. Gut microbiota composition is mostly modulated by diet, and gut microorganisms communicate with the different organs and tissues of the human host by synthesizing [...] Read more.
It is widely recognized that the microorganisms inhabiting our gastrointestinal tract—the gut microbiota—deeply affect the pathophysiology of the host. Gut microbiota composition is mostly modulated by diet, and gut microorganisms communicate with the different organs and tissues of the human host by synthesizing hormones and regulating their release. Herein, we will provide an updated review on the most important classes of gut microbiota-derived hormones and their sensing by host receptors, critically discussing their impact on host physiology. Additionally, the debated interplay between microbial hormones and the development of cardiovascular disease will be thoroughly analysed and discussed. Full article
(This article belongs to the Special Issue Endocrine Dyscrasia and Nutritional Regulation)
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