Iodine: Critical Nutrients for Health throughout Life
A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Micronutrients and Human Health".
Deadline for manuscript submissions: closed (22 December 2021) | Viewed by 13284
Special Issue Editors
Interests: thyroid; ovary; endocrinology; cancer; diabetes
Special Issue Information
Dear Colleagues,
The iodide atom (I-) has a crucial role in earth biology and as an essential micronutrient during all life stages in humans and vertebrates. Iodine is the main component of thyroid hormones, which are critical for human life since they play an essential role in development, growth, metamorphosis, and metabolism. In addition, iodine has a role as a protective agent. Its reducing properties act as antioxidants against radical oxygen species (ROS), and its conversion to hypoiodite has important properties as a bactericide as well as antiviral agent.
Iodine is a scarce element on the Earth’s surface. Rain and glaciations have carried it from the Earth's crust to the oceans for millions of years. Adequate levels of body iodine are essential in human biology and vary throughout life. Iodine deficiency disorders (IDDs) are a major public health problem worldwide, leading to serious health issues such as goiter, hypothyroidism, congenital abnormalities, impaired cognitive development, mental retardation, and even cretinism in newborns whose mothers were iodide deficient during pregnancy. On the opposite spectrum, excess iodine has been associated with conditions such as hypothyroidism and hyperthyroidism. IDD can be prevented with an adequate iodine diet, so an early diagnosis is essential to avoid its effects.
Iodide and thyroid hormone transport and synthesis are altered by environmental exposition to chemical disruptors that initiate or exacerbate problems associated with iodine deficiency disorders, especially during the stages of pregnancy and lactation.
This Special Issue entitled “Iodine: Critical Nutrients for Health throughout Life” aims to bring together high-quality multidisciplinary up-to-date original and review articles on the role of iodine in human pathophysiologic conditions.
Dr. Antonio De La Vieja
Dr. Susana Ares
Guest Editors
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Keywords
- Iodine nutrition
- Iodine in health
- Iodine homeostasis
- Iodide transporters
- Iodide deficiency disorders
- Congenital hypothyroidism
- Iodine epidemiology
- Iodine in evolution
- Iodide transport disruptors
- Thyroid hormone disruptors
- Cancer
- Role of iodide thyroid hormone synthesis and secretion
- Autoimmune thyroid diseases
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