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Nutrition and Menopause: State of the Science

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Nutrition in Women".

Deadline for manuscript submissions: closed (28 February 2023) | Viewed by 4543

Special Issue Editors


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Guest Editor
School of Nursing, Columbia University, New York, NY 10032, USA
Interests: menopause; FSH; estrogen; reproductive neuroendocrinology; vasomotor symptoms; women's health; black cohosh; clinical studies

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Guest Editor
Pennington Biomedical Research Center, Baton Rouge, LA, USA
Interests: menopause; aging; weight gain; obesity; adipose tissue; whole-body metabolism

Special Issue Information

Dear Colleagues,

Menopause marks the natural end of the reproductive life span when a woman's menstrual cycle permanently ceases due to progressive ovarian failure. The age at which natural menopause occurs is 51.4 years, varies widely from 40 to 60 years, and is influenced by a variety of biologic, genetic, and lifestyle factors.

In the years preceding menopause, known as the menopause transition (or perimenopause), there are distinct hormonal changes that are associated with menopausal symptoms (e.g., hot flashes, poor sleep, mood swings, and muscle aches and pains) and physical changes (e.g., vaginal atrophy, bone loss) that reduce a woman’s overall quality of life. Metabolic effects, such as adverse lipid profiles, insulin resistance, and disturbances in energy metabolism, can lead to weight gain (particularly abdominal fat) and the development of obesity-related conditions such as type 2 diabetes and cardiovascular disease. These changes can persist into the postmenopausal years and carry life-long repercussions. Taken together, the importance of nutrition and dietary interventions to offset the decline in ovarian function during menopause and beyond may have considerable benefits, yet rigorous research is lacking.

For this Special Issue, we invite the submission of evidence-based manuscripts, reviews, or meta-analyses that focus on the role of nutrition and dietary interventions in the menopause experience. Manuscripts that explore such questions in different populations such as women of color, as well as women with obesity, and cancer are of special interest. Publications that address the hormonal and metabolic effects of nutrition and dietary trials across the range of weight loss and nutrient modalities will be considered.

Prof. Dr. Nancy King Reame
Prof. Dr. Kara Marlatt
Guest Editors

Manuscript Submission Information

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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nutrients is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • menopause
  • nutrition
  • weight gain
  • obesity
  • hot flashes
  • dietary interventions

Published Papers (2 papers)

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Research

17 pages, 313 KiB  
Article
Frequency of Phytoestrogen Consumption and Symptoms at Midlife among Bangladeshis in Bangladesh and London
by Lynnette Leidy Sievert, Taniya Sharmeen, Khurshida Begum, Shanthi Muttukrishna, Osul Chowdhury and Gillian R. Bentley
Nutrients 2023, 15(17), 3676; https://doi.org/10.3390/nu15173676 - 22 Aug 2023
Cited by 2 | Viewed by 1311
Abstract
There is a longstanding interest in the relationship between diet and hot flash symptoms during midlife, especially in whether phytoestrogens ease menopausal symptoms. The purpose of this study was to examine hot flashes, night sweats, trouble sleeping, and vaginal dryness in relation to [...] Read more.
There is a longstanding interest in the relationship between diet and hot flash symptoms during midlife, especially in whether phytoestrogens ease menopausal symptoms. The purpose of this study was to examine hot flashes, night sweats, trouble sleeping, and vaginal dryness in relation to the intake of foods rich in phytoestrogens among Bangladeshi women aged 35 to 59 years who were living either in Sylhet, Bangladesh (n = 157) or as migrants in London (n = 174). Consumption ranges for phytoestrogens were constructed from food frequencies. We hypothesized that diets rich in isoflavones, lignans, and coumestrol would be associated with lower symptom frequencies. However, adjusted logistic regression results showed that with each incremental increase in general phytoestrogen consumption (scale of 0 to 10), the likelihood of hot flashes increased by 1.4%. Each incremental increase in lignan consumption raised the likelihood of hot flashes by 1.6%. In contrast, the odds of vaginal dryness decreased by 2%, with each incremental increase in phytoestrogen and lignan consumption, and by 4%, with each incremental increase in isoflavone consumption. Night sweats and trouble sleeping were not associated with phytoestrogen intake in logistic regressions. Our findings add to the conflicting data on relationships between phytoestrogens and symptoms associated with menopause. Full article
(This article belongs to the Special Issue Nutrition and Menopause: State of the Science)
14 pages, 633 KiB  
Article
Meal-Based Intervention on Health Promotion in Middle-Aged Women: A Pilot Study
by Jinyoung Shon, Yehee Seong, Yeji Choi, Yeri Kim, Mi Sook Cho, Eunhee Ha, Oran Kwon, Yuri Kim, Yoon Jung Park and Yangha Kim
Nutrients 2023, 15(9), 2108; https://doi.org/10.3390/nu15092108 - 27 Apr 2023
Viewed by 2372
Abstract
Middle-aged women belong to a risk group for metabolic dysregulation and menopausal symptoms, mainly due to a dramatic hormonal shift. Supplementation with functional compounds or a single nutrient has been dominantly explored as a nutritional approach for improving aging-related health parameters. However, a [...] Read more.
Middle-aged women belong to a risk group for metabolic dysregulation and menopausal symptoms, mainly due to a dramatic hormonal shift. Supplementation with functional compounds or a single nutrient has been dominantly explored as a nutritional approach for improving aging-related health parameters. However, a meal-based approach might be another strategy for promoting the overall health of the target population. This pilot study aimed to develop a meal-based intervention for middle-aged women and to evaluate its potential health benefits. Considering the nutrient intake status of Korean middle-aged women, diets enriched with four major nutrients (isoflavone, omega-3, fiber, and calcium) were designed and provided to forty-nine women aged 50 to 65 with mild levels of menopausal symptoms for 8 weeks. In the post-intervention phase, they showed reduced body weight and body fat, and improved biochemical metabolic parameters with decreased levels of cholesterol, low-density lipoprotein-cholesterol, ApoB, and fasting insulin. Moreover, bone resorption markers and menopause symptoms were lower in the post-intervention phase. In conclusion, the meal-based intervention might be a prominent strategy for overall health promotion in relatively healthy middle-aged women and further investigation is needed to test its efficacy with a randomized controlled study. Full article
(This article belongs to the Special Issue Nutrition and Menopause: State of the Science)
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