Novel Therapeutic Approach to Inflammation and Pain

Dear Colleagues,

Inflammation and pain are two closely related issues that are often intricately linked in certain pathologies and are therefore frequently studied together in scientific research. It has been determined that they are interconnected by a complex signaling network based on a variety of molecules, receptors, and cellular pathways, which play fundamental roles in the onset and development of pathological conditions such as, for example, cancer, osteoarthritis, metabolic disorders, and autoimmune disease. However, although many advances have been made in this research field, the whole mechanisms responsible for inflammatory and painful signaling have not been fully clarified. Moreover, from a therapeutical perspective, currently available analgesic and anti-inflammatory drugs are often characterized by various side effects that limit their clinical administration. In this context, understanding these mechanisms and identifying new therapeutic targets would pave the way for new discoveries in the pharmaceutical field to provide innovative alternatives to inflammation and pain treatment. At the same time, it is important to discover and develop new molecules with increasingly minimal side effects.

In this Special Issue of Pharmaceutics, we invite authors to submit original research articles or reviews in the fields of pain and inflammation. Research areas may include (but are not limited to) the following topics:

• Study of alternative targets or novel therapeutic strategies;
• New pharmaceutical formulations;
• Drug delivery systems as well as drug repositioning approaches.

Hoping for your active participation, we look forward to receiving your contributions.

Dr. Roberto Mattioli
Dr. Alessia Mariano
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pharmaceutics is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.