Approaches to Individualized Drug Therapy Based on Population Pharmacometrics
A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Pharmacokinetics and Pharmacodynamics".
Deadline for manuscript submissions: closed (31 March 2023) | Viewed by 15890
Special Issue Editors
Interests: pharmacometrics; modeling; nanoformulation; drug delivery; lymph; herbal medicine; clinical study
Special Issues, Collections and Topics in MDPI journals
Interests: pharmacokinetics; pharmacodynamics; toxicometrics; risk assessment; physiologically based modeling; lymphatic delivery; nanoformulation and evaluation; bioanalytical method development and validation
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Pharmacometrics modeling plays a leading role in the journey towards personalized therapy by quantitatively predicting the correlations of the various factors influencing changes in drug behavior in in vivo systems. The demand for physiologically based pharmacokinetic–pharmacodynamic modeling techniques, including those for the pharmacokinetic–pharmacodynamic modeling of whole populations, is increasing in the pharmaceutical and clinical industries, with the ultimate aim of improving effects through optimal drug therapy. Pharmacometrics modeling is clearly an important tool in drug development and for the development of effective clinical applications.
The purpose of this Special Issue is to collect approaches to individualized drug therapy based on population pharmacometrics. This issue will not be limited to population modeling, but will also include work on the prediction of drug behavior through mathematical modeling and model simulations. In addition, extended application studies on model-based clinical dosing systems and regimens are also welcome. This Special Issue is an opportunity to move one step closer to precision medicine based on quantitative modeling techniques.
Prof. Dr. Yong-Bok Lee
Dr. Seung-Hyun Jeong
Guest Editors
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Keywords
- population pharmacokinetics
- population pharmacodynamics
- physiologically based modeling
- model simulation
- precision medicine
- dosage regimen
- clinical study
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