Advances in Scaffolds for Dental and Periodontal Tissue Regeneration

A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Pharmaceutical Technology, Manufacturing and Devices".

Deadline for manuscript submissions: closed (10 September 2024) | Viewed by 1151

Special Issue Editors


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Guest Editor
Department of Prosthodontics, School of Dentistry, Faculty of Health Sciences, Aristotle University of Thessaloniki, GR-54124 Thessaloniki, Greece
Interests: dentistry; glass ceramics; glass science and technology; glass chemistry; ceramics; sol-gel; composites; implant dentistry; restorative dentistry; esthetic dentistry; fixed prosthodontics; aesthetic dentistry; dental materials; implant dentistry, bone grafts and related treatments; materials; coating; mechanical properties; material characterization; materials processing; composite material; advanced materials; tissue regeneration; microstructure; ceramic materials; material characteristics; nanomaterials
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
Department of Prosthodontics, School of Dentistry, Faculty of Health Sciences, Aristotle University of Thessaloniki, GR-54124 Thessaloniki, Greece
Interests: scaffolds; tissue regeneration; tissue engineering; stem cells; biomaterials; biocompatibility; regenerative medicine; 3D cell culture; stem cell differentiation; stem cell culture; fixed prosthodontics; removable prosthodontics; bioceramics; cell biology; prosthodontics; implant prosthodontics; bone tissue engineering; biotechnology; scaffold; 3D bioreactor culture; 3D culture

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Guest Editor
School of Dentistry, European University of Cyprus, Nicosia, Cyprus
Interests: oral rehabilitation; scaffolds; dental prosthesis; tissue regeneration; tissue engineering; stem cells; biomaterials; biocompatibility; regenerative medicine; 3D cell culture; stem cell differentiation; stem cell culture; fixed prosthodontics; removable prosthodontics; bioceramics; cell biology; prosthodontics; implant prosthodontics

Special Issue Information

Dear Colleagues,

There is an increasing need for dental and periodontal tissue regeneration. The intricate structure of dental tissues presents several challenges for the field of regenerative dentistry, despite significant advancements in regenerative therapies. Clinical dentists, cellular biologists, and material scientists are working collaboratively to develop strategies and discover remedies for dental tissue regeneration.

This Special Issue aims to highlight prevailing research regarding the development of functional biomaterials and extracellular matrices (ECMs) for the repair and regeneration of dental and surrounding tissues including enamel, dentin, pulpal tissue, periodontal ligament, and alveolar bone.

These tailored functional biomaterials and ECMs can be fabricated in a variety of forms, including cell-encapsulating hydrogels, dense composites, porous scaffolds, decellularized matrices, and bioprinted 3D structures. The field also includes cutting-edge technologies for delivering drugs, biomolecules, and ions that can promote cellular responses such as proliferation, migration, and differentiation to specific lineages, all of which are beneficial for the healing and regeneration of dental and surrounding tissues.

Dr. Eleana Kontonasaki
Dr. Maria Bousnaki
Dr. Christina Hadjichristou
Guest Editors

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Keywords

  • scaffolds
  • hydrogels
  • membranes
  • extracellular matrix (ECM)
  • 3D printing
  • bioprinting
  • cell sheets
  • tissue engineering and regenerative medicine (TERM)
  • regeneration
  • dentin
  • enamel
  • pulp
  • dentin–pulp complex
  • cementum
  • alveolar bone
  • periodontal ligament
  • stem cells
  • bioactive molecules
  • dentin matrix proteins

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Published Papers (1 paper)

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Research

16 pages, 3117 KiB  
Article
Optimization of Sodium Iodide-Based Root Filling Material for Clinical Applications: Enhancing Physicochemical Properties
by Hye-Shin Park, Yu-Jin Kim, Soo-Jin Chang, Hae-Hyoung Lee, Mi-Ran Han, Joon-Haeng Lee, Jong-Soo Kim, Jong-Bin Kim, Ji-Sun Shin and Jung-Hwan Lee
Pharmaceutics 2024, 16(8), 1031; https://doi.org/10.3390/pharmaceutics16081031 - 2 Aug 2024
Viewed by 706
Abstract
Premature loss of root canal-treated primary teeth has long been a concern in dentistry. To address this, researchers developed a sodium iodide-based root canal-filling material as an alternative to traditional iodoform-based materials. The goal of this study was to improve the physicochemical properties [...] Read more.
Premature loss of root canal-treated primary teeth has long been a concern in dentistry. To address this, researchers developed a sodium iodide-based root canal-filling material as an alternative to traditional iodoform-based materials. The goal of this study was to improve the physicochemical properties of the sodium iodide-based material to meet clinical use standards. To resolve high solubility issues in the initial formulation, researchers adjusted component ratios and added new ingredients, resulting in a new paste called L5. This study compared L5 with L0 (identical composition minus lanolin) and Vitapex as controls, conducting physicochemical and antibacterial tests. Results showed that L5 met all ISO 6876 standards, demonstrated easier injection and irrigation properties than Vitapex, and exhibited comparable antibacterial efficacy to Vitapex, which is currently used clinically. The researchers conclude that if biological stability is further verified, L5 could potentially be presented as a new option for root canal-filling materials in primary teeth. Full article
(This article belongs to the Special Issue Advances in Scaffolds for Dental and Periodontal Tissue Regeneration)
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