Novel Approaches to Drug Delivery in Ophthalmic Disorders
A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Drug Delivery and Controlled Release".
Deadline for manuscript submissions: 31 October 2025 | Viewed by 46
Special Issue Editors
Interests: eye diseases; ocular drug delivery; corneal lenticule; stem cells; rhNGF
Interests: eye diseases; ocular drug delivery; corneal lenticule; stem cells; rhNGF
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The eyes are one of the most important organs of the human body and they can be affected by various diseases. However, the eye’s complex anatomy, including barriers such as the corneal epithelium, blood–retinal barrier, and tear dynamics, presents significant obstacles to effective drug delivery. For these reasons, conventional methods like topical drops and systemic administration often fail to achieve optimal therapeutic concentrations at the target sites. Therefore, there is a pressing need to develop more advanced delivery systems to overcome bioavailability challenges and sustain effective drug concentrations at the target cells or tissues for an appropriate duration.
This Special Issue aims to highlight recent research and advancements in ocular drug delivery systems, empathizing innovative strategies such as nanoparticle carriers, injectable hydrogels, sustained-release implants, and gene delivery systems.
By bringing together a collection of cutting-edge studies, this Special Issue seeks to provide a wide range of original research articles and reviews on the current state of research into the development of ocular drug delivery systems. It will serve as a valuable resource for scientists, clinicians, and pharmaceutical developers dedicated to improving treatment outcomes for both anterior and posterior segment ocular diseases.
Dr. Letizia Pelusi
Dr. Domitilla Mandatori
Guest Editors
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Keywords
- eye diseases
- ocular drug delivery
- ocular barrier
- conventional therapies
- innovative technologies
- nanoparticle carriers
- injectable hydrogels
- ocular implants
- gene therapy in ophthalmology
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