Long Acting Drug Delivery Formulations
A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Physical Pharmacy and Formulation".
Deadline for manuscript submissions: 20 May 2025
Special Issue Editor
Interests: microencapsulation; nanoemulsions; biopharmacy; formulation; pharmaceutical engineering
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Long-acting drug delivery formulations are specialized pharmaceutical systems designed to release active drug compounds gradually over an extended period, ranging from weeks to months or even years, depending on the formulation. The goal is to maintain therapeutic drug levels in the body with fewer doses, enhancing patient compliance and therapeutic outcomes. These formulations reduce the need for frequent dosing by controlling the release rate of the drug and often employ advanced drug delivery technologies such as biodegradable polymers, microspheres, liposomes, or implants.
Their benefits include the following:
- Improved patient adherence by reducing the dosing frequency.
- Steady-state drug levels, minimizing the peaks and troughs associated with frequent dosing.
- Reduced side effects due to consistent drug release.
- Targeted delivery to specific tissues in some formulations, enhancing efficacy and minimizing off-target effects.
These formulations are widely used in treating chronic conditions, where long-term drug administration is necessary, such as in hormonal therapies, psychiatric medications, or pain management.
In this Special Issue, original research articles and reviews are welcome. I look forward to receiving your contributions.
Prof. Dr. Thierry Vandamme
Guest Editor
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Keywords
- improvement in patient adherence
- steady state
- drug bioavailability
- reduced side effect
- targeted delivery
- long acting
- sustained release
- prolonged release
- pulse release
- compliance
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