Development and Evaluation of Inhalable Dry Powder Formulations
A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Physical Pharmacy and Formulation".
Deadline for manuscript submissions: closed (28 February 2023) | Viewed by 22694
Special Issue Editors
Interests: respiratory drug delivery; inhalation aerosol medicine; lung surfactant; targeted drug delivery systems; controlled release drug delivery; sustained-release peptide injectibles; CNS peptide therapeutics nose-to-brain delivery
Interests: pulmonary delivery; dry powder inhalations; targeted drug delivery systems; particle engineering; spray drying; surface characterization; physicochemical characterization; respirable size particle dissolution
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Respiratory drug delivery is an important route for the administration of treatment and prevention of diseases of the respiratory tract (nasal and pulmonary regions), and for delivering drugs non-invasively to the central nervous system (CNS). Pulmonary drug delivery has recently gained a significant importance in the therapeutic field due to the various advantages, such as pain-free administration, targeted drug delivery with minimum systemic exposure, rapid onset of action, reduced enzymatic degradation, high drug-concentrations in the lungs, and avoidance of hepatic first-pass metabolism compared to the other conventional routes of administration. Formulations including biologicals have shown an increased stability when they are in solid-state rather than liquid formulations, making dry powder inhalers (DPIs) the more preferred formulation for pulmonary drug delivery. The aerodynamic diameter, along with other features of the particles, plays a key role in the deposition of aerosols in the lungs; therefore, it is important to engineer the particles using the right technique. This Special Issue focuses on the design and development of innovative dry powder formulations as inhalation aerosols by the lung and nasal routes of administration.
Prof. Dr. Heidi M. Mansour
Dr. Basanth Babu Eedara
Guest Editors
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Keywords
- respiratory delivery
- dry powder inhalation
- particle engineering design
- physicochemical characterization
- aerosolization
- lung delivery
- nasal delivery
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