Silica Nanoparticles as Promising Theranostic Platform

A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Nanomedicine and Nanotechnology".

Deadline for manuscript submissions: closed (31 July 2023) | Viewed by 2634

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Department Inorganic Chemistry, Physical Chemistry and Electrochemistry, Faculty of Chemical Engineering and Biotechnologies, University Politehnica of Bucharest, 1-7 Gh. Polizu Street, 011061 Bucharest, Romania
Interests: drug-delivery systems; mesoporous materials; inorganic nanoparticles
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Guest Editor
Department Inorganic Chemistry, Physical Chemistry and Electrochemistry, Faculty of Chemical Engineering and Biotechnologies, University Politehnica of Bucharest, 1-7 Gh. Polizu Street, 011061 Bucharest, Romania
Interests: mesoporous silica nanomaterials; drug delivery systems

Special Issue Information

Dear Colleagues,

Research interests in the medical field currently focus on the introduction of nanotechnology into the diagnosis and therapy of patients. The features of mesoporous silica nanoparticles, such as tunable pore size or particle shape and highly versatile surface properties, make them an ideal candidate for the identification and accommodation of biologically relevant molecules, thus assisting in patient diagnosis and treatment therapy.

This Special Issue aims to publish papers regarding the recent advances of mesoporous silica nanoparticles used in biomedical applications, such as drug delivery systems, targeted drug delivery, biomedical imaging, tissue engineering or pharmaceutical formulations based on silica nanoparticles.

Research areas include, but are not limited to, the design of silica nanoparticles or hybrid silica-based systems as nanoplatforms for various biologically active substances for diagnostics and treatment. 

We invite you to submit original research, communications or critical review papers within the scope of this Special Issue.

We hope that this Special Issue will be a valuable source of progress in the development of silica-based theranostic platforms.

Prof. Dr. Daniela Berger
Dr. Mihaela Deaconu
Guest Editors

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Keywords

  • mesoporous silica nanoparticles
  • functionalized silica nanoparticles
  • hybrid nanomaterials
  • nanocomposites
  • theranostics
  • drug delivery systems
  • synergic delivery systems
  • tissue engineering
  • targeted therapy
  • biomedical imaging
  • stimuli-responsive nanomaterials

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Published Papers (1 paper)

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18 pages, 4697 KiB  
Article
Novel Collagen-Polyphenols-Loaded Silica Composites for Topical Application
by Mihaela Deaconu, Ana-Maria Prelipcean, Ana-Maria Brezoiu, Raul-Augustin Mitran, Gabriela Isopencu, Cristian Matei and Daniela Berger
Pharmaceutics 2023, 15(2), 312; https://doi.org/10.3390/pharmaceutics15020312 - 17 Jan 2023
Cited by 8 | Viewed by 2223
Abstract
Lesions can affect skin functions and cause a simple issue, such as dehydration, or more challenging complications, such as bacterial infections. The purpose of this study was to design composites for topical application that can prevent and/or assist in bacterial infections and support [...] Read more.
Lesions can affect skin functions and cause a simple issue, such as dehydration, or more challenging complications, such as bacterial infections. The purpose of this study was to design composites for topical application that can prevent and/or assist in bacterial infections and support cell regeneration using natural components. A polyphenolic extract obtained from Salvia officinalis was embedded in functionalized mesoporous silica nanoparticles for better stability, followed by their distribution into a collagen porous scaffold. The resulting polyphenols-loaded MSN exhibited enhanced antibacterial activity and good cytocompatibility. Improved thermal stability of the collagen porous scaffold was obtained due to the presence of the functionalized MSN. For the first time, collagen-polyphenols-loaded silica composites were reported in the literature as potential wound dressings. The newly developed composites showed excellent sterility. Full article
(This article belongs to the Special Issue Silica Nanoparticles as Promising Theranostic Platform)
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