Optimization of Tuberculosis Drugs and Treatment Strategies to End Tuberculosis (TB)

Dear Colleagues,

Tuberculosis remains a global health tread. Significant progress has been made in the development of three new anti-TB drugs (bedaquiline, delamanid and pretomanid), and several other drugs are undergoing preclinical or clinical development. Strategies to develop shorter regimens using different dosing strategies of available TB drugs have been evaluated in large trials for preventative treatment, drug-susceptible TB as well as drug-resistant TB. In addition, in vitro and in vivo models as well as modeling and simulation have resulted in a better understanding of how treatment outcome can be improved. This Special Issue of Pharmaceutics is dedicated to presenting the latest evidence and information on new drugs and drug trials, drug dose optimization strategies and tools to support the management of TB treatment to ensure that it is safe and effective.

Prof. Dr. Jan-Willem Alffenaar
Dr. Lina Davies Forsman
Dr. Jin-Gun Cho
Dr. Andrew Burke
Guest Editors

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