Novel Pharmaceuticals Development and Delivery Systems for the Treatment of Parasitic Diseases, 2nd Edition
A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Drug Targeting and Design".
Deadline for manuscript submissions: 31 December 2024 | Viewed by 2973
Special Issue Editor
2. Centre for Parasite Biology and Immunology, Department of Infectious Diseases, National Health Institute Dr. Ricardo Jorge, Rua Alexandre Herculano 321, 4000-055 Porto, Portugal
Interests: carcinogenesis; helminth-associated carcinogenesis; combine therapy; immunotherapy; protein recombinant; parasites; schistosoma; opisthorchis
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Parasitic infections such as malaria, schistosomiasis, and leishmaniasis, among others, remain a major public health problem causing substantial mortality and morbidity worldwide. Antiparasitic drugs are available, but they are not ideal and present major disadvantages. Furthermore, there is a real concern regarding the development of drug resistance (e.g., primaquine for malaria). Few novel antiparasitic drugs have emerged in recent decades, and the discovery and development of novel antiparasitic drugs are urgently needed. Strategies such as combinations of existing drugs, improvements to known drugs, de novo discovery, and/or the exploration of natural bioactive compounds, among others, should be explored to improve the treatment of parasitic infections and prevent the development of drug resistance.
This Special Issue aims to discuss strategies for the discovery and development of novel treatments for parasitic diseases, as well as advanced drug delivery technology. The design and synthesis of novel drugs or drug derivatives and their antiparasitic activities, structure–activity relationships (SARs), the use of bioinformatics tools (or others) for the discovery of potential drugs, and natural compounds as sources of antiparasitic drugs will be addressed here. Colleagues are invited to submit original research papers, communications, or review articles to this Special Issue.
Dr. Maria João Castro Gouveia
Guest Editor
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Keywords
- parasites
- drug synthesis and discovery
- natural bioactive compounds
- drug combinations
- parasitic diseases
- neglected tropical diseases
- novel therapeutic strategies
- optimization
- formulations
- mechanism of action
- screening assays
- pharmacodynamics
- pharmacokinetics
- drug resistance
- antiparasitic activity
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