Advances in Co-Amorphous Drug Formulations
A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Physical Pharmacy and Formulation".
Deadline for manuscript submissions: closed (20 February 2021) | Viewed by 11554
Special Issue Editor
Special Issue Information
Dear Colleagues,
Since the concept of co-amorphization was introduced more or less a decade ago, the amount of research activity around the topic has increased exponentially. The co-amorphous approach has become a preferred alternative to polymeric solid dispersions in the stabilization of the amorphous state and in improving the dissolution rate of drugs. Along the way, our understanding of the formation of co-amorphous systems, the selection of co-formers, interactions between the mixture components, dissolution enhancement and physical stability has increased. However, challenges remain, as more research is required on the processability of co-amorphous mixtures into final dosage forms. In addition to oral administration, alternative routes, such as pulmonary, may be used for delivering co-amorphous formulations. Therefore, this Special Issue welcomes articles that cover all aspects of the design, manufacturing, characterization and final formulation of co-amorphous mixtures, aiming to reflect their current status and highlight the future prospects and challenges of amorphous drug formulations on their way to becoming medicinal products.
Dr. Riikka Laitinen
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pharmaceutics is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- co-amorphous
- dissolution
- supersaturation
- stability
- bioavailability
- solid-dosage form
- solid-state characterization
