Targeted and Bioresponsive Drug Delivery System for Antimicrobial Resistance
A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Drug Delivery and Controlled Release".
Deadline for manuscript submissions: closed (30 August 2022) | Viewed by 506
Special Issue Editors
Interests: bioresponsive polymer; drug delivery; cancer therapy; uncontrolled inflammation diseases; antimicrobial resistance
Interests: bacteria; antimicrobial resistance; antimicrobial agents; antimicrobial peptides; infectious disease
Special Issue Information
Dear Colleagues,
When pathogens, especially bacteria, are no longer sensitive to medicines because of misuse and overuse, antimicrobial resistance (AMR) will occur, which makes the infections harder to treat and increases the severity of their threat to human health. The traditional strategy is to develop new antibiotics to tackle the “superbugs”. However, in the future, “superbugs” are going to emerge. This dilemma leads to a vicious circle. Is there is more efficient and effective therapeutic strategy to treat infectious diseases?
Targeted and bioresponsive drug delivery systems (TB-DDS) are gaining increasing attention and being thoroughly investigated as a promising means of overcoming AMR. Targeted strategies can send the antibiotic to the specific infection site, not the healthy sites as the scatter-gun approach can due to being “off-target”. Bioresponsive drug delivery can make the system respond to special cues at the infection site to release the antibiotic “on-demand”. Herein, the TB-DDS are used as “precision medicine”. Furthermore, some “smart” carriers with antimicrobial activity make the TB-DDS show synergistic effect combined with antibiotics.
Therefore, we are pleased to invite you to submit your works related to the development of TB-DDS based on inorganic materials, organic materials and hybrid materials as well as “free-carrier” DDS, submitted as full articles, letters, reviews and other forms. In this Special Issue, research areas may include but are not limited to the following: targeted or bioresponsive drug delivery systems for AMR, infection treatment, wound healing, and penetration of biofilm.
We look forward to receiving your contributions.
Dr. Canyang Zhang
Dr. Federica Armas
Dr. Juan Li
Guest Editors
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Keywords
- targeted drug delivery
- bioresponsive drug delivery
- antimicrobial resistance
- anti-infection
- controlled release
- pharmaceutical engineering
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