Novel Approaches for Overcoming Biological Barriers
A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Biopharmaceutics".
Deadline for manuscript submissions: closed (20 July 2022) | Viewed by 50257
Special Issue Editors
Interests: biomaterials; biologics; long-term drug delivery; nanomedicine; hydrogels; ocular; inner ear
Special Issues, Collections and Topics in MDPI journals
Interests: vaccine; human vaccines; vaccine development; formulation development; attenuated vaccine; viral vaccines; bacterial vaccines; subunit vaccines; pediatric vaccines; COVID vaccines; measles and rubella vaccines; rotavirus vaccine; HPV vaccine; Shigella vaccine; Salmonella vaccine; combination vaccines; polio vaccine; stability study; potency assay; analytical assays; preclinical study; immunogenicity study; biophysical characterization; adjuvants; scale-up; technology transfer
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Biological barriers act as the key interface between organs and tissues by protecting them against “foreign materials” and allowing only specific molecules to cross, e.g., by receptor-regulated transcytosis. The selective permeability of biological barriers and the growing trend to use large molecules as next generation therapeutics makes it challenging to deliver drugs to specific targets in our body. Use of physical enhancement methods, chemical permeation enhancers, activation/inhibition of transports, biomolecules, nanotechnology, microneedles, biomimetics, and engineered biomaterials, etc., have been demonstrated to allow overcoming biological barriers. This Special Issue serves to provide readers with an overview of the novel approaches and new therapeutic modalities being used to target sites across biological barriers. We are interested in articles related to quantitative and mechanistic studies using in vitro models, in vivo trials, and translational challenges for enhancing drug delivery across biological barriers and for applications in the pharmaceutical industry.
Dr. Vibhuti Agrahari
Dr. Prashant Kumar
Guest Editors
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Keywords
- drug delivery
- transdermal transport
- blood–brain barrier
- permeation enhancers
- transporters
- nanoparticles
- microneedles