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Advances in Green Chemistry Processes: Isolation, Characterization and Applications of...
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Advances in Green Chemistry Processes: Isolation, Characterization and Applications of Plant-Derived Bioactive Compounds

A special issue of Processes (ISSN 2227-9717). This special issue belongs to the section "Chemical Processes and Systems".

Deadline for manuscript submissions: 30 January 2025 | Viewed by 1178

Special Issue Editors

Prof. Dr. Jasna Čanadanović-Brunet

E-Mail Website
Guest Editor
Department of Applied and Engineering Chemistry, Faculty of Technology Novi Sad, University of Novi Sad, Bulevar cara Lazara 1, 21000 Novi Sad, Serbia
Interests: polyphenols; free radicals; antioxidant bioactivity; natural products; structural analysis; nutrients and bioactive compounds; liquid chromatography; spectrometry; bioactivity; bioaccessibility and bioavailability; added-value products
Special Issues, Collections and Topics in MDPI journals
Dr. Olja Šovljanski

E-Mail Website
Guest Editor
Faculty of Technology Novi Sad, Department of Biotechnology, University of Novi Sad, Bulevar Cara Lazara 1, 21000 Novi Sad, Serbia
Interests: antimicrobial substance; alternative crops; food microbiology; antimicrobial activity; biowaste; bioactive compounds; natural pigments; antioxidant acitivity; food; antioxidants; encapsulation; plant extract; bioactivity; HPLC; antimicrobials
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Growing public and consumer demand, accompanied by ongoing research efforts to investigate the qualities and prospective applications of nutraceutical substances, have led to an increased interest in processes related to bioactive compounds, phytochemicals, and functional foods. The transparent diversity of natural product chemistry's sources reveals its beauty. Also the processing of plants results in high amounts of bio-wastes (by-products) which causes economic and ecological deficit problems. Today, the biowastes are often utilized as feed, and for the preparation of dietary fibre and biofuel through bioconversation processes. These products are also promising sources of bioactive antioxidants and colour-giving compounds, which could be used in food, pharmaceutical and cosmetic industries. To isolate, identify, and use bioactive chemicals from natural sources, extraction and conversation processes are an important phase along with the screening of their bioactivities and ultimately the elucidation of structure–activity relationships. In this context, the current Special Issue is open to scientific research submissions correlated to developing, upgrading and mathematical analyses obtaining plant-derived and health-promoting bioactive compounds. Characterization of these bioactives can provide functional benefits that play a crucial role in disease prevention caused by oxidative stress. A special emphasis will be given to eco-friendly technologies and processes with a deep insight into bioactivities characterization using analytical methodologies, in vitro assays, as well as in silico and in vivo studies to evaluate pro-healthy effects, including anti-inflammatory, antimicrobial, antioxidant properties and application safety, addressing potential final applications.

Potential topics include but are not limited to the following:

  • Extraction, preservation, and identification/quantification of plant-derived bioactives
  • New findings on the structure, functionality, nutrition, and application of natural products.
  • New trends in the application of eco-friendly techniques to extract bioactive compounds.
  • Isolation and characterization of nutritional components from plant extracts
  • Characterization of extracts and their possible uses.
  • Methods to improve the bioaccessibility and bioavailability of the targeted compounds.
  • Methods to explore the antioxidant and anti-inflammatory activity of bioactive compounds in food
  • Antimicrobial effects of bioactive components derived from food, and their interaction with gut microbiome and their health outcomes
  • Antidiabetic and antiobesity effects of bioactive compounds
  • In vitro and in vivo evaluation of the function of plant-derived bioactives
  • Food bioactive components and their functionalities in health problems.

Prof. Dr. Jasna Čanadanović-Brunet
Dr. Olja Lj. Šovljanski
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Processes is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • secondary metabolites
  • bioactive compounds
  • characterization of bioactive compounds
  • innovative food
  • plant natural resources
  • by-products
  • antioxidants
  • green extraction
  • chromatography
  • health benefits
  • bioactivity
  • bioavaiability

Published Papers (2 papers)

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Research

22 pages, 3255 KiB  
Article
Supramolecular Solvent-Based Extraction of Microgreens: Taguchi Design Coupled-ANN Multi-Objective Optimization
by Anja Vučetić, Lato Pezo, Olja Šovljanski, Jelena Vulić, Vanja Travičić, Gordana Ćetković and Jasna Čanadanović-Brunet
Processes 2024, 12(7), 1451; https://doi.org/10.3390/pr12071451 - 11 Jul 2024
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Abstract
Supramolecular solvent-based extraction (SUPRAS) stands out as a promising approach, particularly due to its environmentally friendly and efficient characteristics. This research explores the optimization of SUPRAS extraction for sango radish and kale microgreens, focusing on enhancing the extraction efficiency. The Taguchi experimental design [...] Read more.
Supramolecular solvent-based extraction (SUPRAS) stands out as a promising approach, particularly due to its environmentally friendly and efficient characteristics. This research explores the optimization of SUPRAS extraction for sango radish and kale microgreens, focusing on enhancing the extraction efficiency. The Taguchi experimental design and artificial neural network (ANN) modeling were utilized to systematically optimize extraction parameters (ethanol content, SUPRAS: equilibrium ratio, centrifugation rate, centrifugation time, and solid-liquid ratio). The extraction efficiency was evaluated by measuring the antioxidant activity (DPPH assay) and contents of chlorophylls, carotenoids, phenolics, and anthocyanidins. The obtained results demonstrated variability in phytochemical contents and antioxidant activities across microgreen samples, with the possibility of achieving high extraction yields using the prediction of optimized parameters. The optimal result for sango radish can be achieved at an ethanol content of 35.7%; SUPRAS: equilibrium ratio of 1 v/v, centrifugation rate of 4020 rpm, centrifugation time of 19.84 min, and solid-liquid ratio of 30.2 mg/mL. The following parameters are predicted for maximal extraction efficiency for kale: ethanol content of 35.64%; SUPRAS: equilibrium ratio of 1 v/v; centrifugation rate of 3927 rpm; centrifugation time of 19.83 min; and solid-liquid ratio of 30.4 mg/mL. Additionally, laboratory verification of predicted SUPRAS parameters showed very low divergency degrees for both microgreens (–3.09 to 2.36% for sango radish, and −2.57 to 3.58% for kale). This potential of SUPRAS extraction, coupled with statistical and computational optimization techniques, can enhance the recovery of valuable bioactive compounds from microgreens and contribute to green extraction applications. Full article
(This article belongs to the Special Issue Advances in Green Chemistry Processes: Isolation, Characterization and Applications of Plant-Derived Bioactive Compounds)
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18 pages, 4673 KiB  
Article
Impact of Storage Conditions on Stability of Bioactive Compounds and Bioactivity of Beetroot Extract and Encapsulates
by Vesna Postružnik, Slađana Stajčić, Dragana Borjan, Gordana Ćetković, Željko Knez, Maša Knez Marevci and Jelena Vulić
Processes 2024, 12(7), 1345; https://doi.org/10.3390/pr12071345 - 28 Jun 2024
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Abstract
(1) Background: In this study, bioactive compounds (phenolics and betalains) extracted from beetroot were stabilized by encapsulation with maltodextrin and soy protein by the freeze drying method. Stability of bioactive compounds and bioactivities in a beetroot extract and encapsulates during 60 days of [...] Read more.
(1) Background: In this study, bioactive compounds (phenolics and betalains) extracted from beetroot were stabilized by encapsulation with maltodextrin and soy protein by the freeze drying method. Stability of bioactive compounds and bioactivities in a beetroot extract and encapsulates during 60 days of storage at 4 °C (without light) and at 25 °C (with and without light) were investigated. (2) Methods: Contents of bioactive compounds and bioactivity (antioxidant activity by DPPH, RP, and ABTS tests; anti-inflammatory and antihyperglycemic activity) were determined. Improvement in stability of bioactives’ content and bioactivity of prepared encapsulates in relation to the extract was observed after storage at room temperature under light conditions. (3) Results: Encapsulation with maltodextrin showed improvement in stability of all studied bioactive parameters, while an encapsulate with soy protein improved stability of bioactives and antioxidant activity compared to the extract. The encapsulated beetroot extract represents a promising food additive for functional foods due to their content of bioactive compounds and consequent bioactivities. Full article
(This article belongs to the Special Issue Advances in Green Chemistry Processes: Isolation, Characterization and Applications of Plant-Derived Bioactive Compounds)
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