Biological Methods of Diagnosis in the Microbiology

Dear Colleagues,

Over time, diagnosis in microbiology has primarily focused on identifying disease-causing microorganisms in clinical specimens using culture methods. However, there have been significant technological advancements in the field, leading to the development of more efficient techniques for detecting and identifying microorganisms. These advancements have revolutionized microbiology laboratory diagnostic tools, particularly in bacteriology, mycology, mycobacteriology, parasitology, and virology. The main objectives of diagnosis in microbiology are to confirm the presence of suspected pathogenic microorganisms in samples from humans, animals, and the environment, and to identify and characterize these organisms. Innovative biological methods, such as nucleic acid amplification-based molecular techniques, enable quick and customizable diagnostic outcomes, benefiting patient care. In addition to detecting, quantifying, and identifying microorganisms, biological methods in microbiology also provide physicians with antimicrobial susceptibility profiles of the identified microorganisms. Furthermore, these technical advances have greatly influenced the physical structure of laboratories, staffing patterns, workflow, and turnaround time.

This Special Issue emphasizes the development of innovative and cost-effective biological diagnostic approaches in the field of microbiology. Topics may include, but are not limited to, methods and applications in the following areas:

• Microorganism culture and identification;
• Direct microorganism identification based on antigen or nucleic acid detection;
• Immunoassay-based diagnostic approaches;
• Omics-based (genomics, proteomics, and metabolomics) diagnosis methods.

Dr. Sazzad Hossen Toushik
Dr. Md. Furkanur Rahaman Mizan
Guest Editors

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• biological techniques
• microbial culture
• microscopy
• biochemical tests
• molecular diagnostics
• hybridization techniques