Green Solvent for Separation and Extraction Processes

A special issue of Processes (ISSN 2227-9717). This special issue belongs to the section "Separation Processes".

Deadline for manuscript submissions: 20 December 2025 | Viewed by 876

Special Issue Editors


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Guest Editor
Department of Biochemical Engineering, School of Chemistry, Federal University of Rio de Janeiro, Rio de Janeiro 21949-900, RJ, Brazil
Interests: bioseparation; enzymatic extraction; protein purification; green solvents; upstream process; downstream process; liquid-liquid bioextraction; fermentation
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Department of Biochemical Engineering, School of Chemistry, Federal University of Rio de Janeiro, Rio de Janeiro 21949-900, RJ, Brazil
Interests: green solvents; ionic liquids; deep eutectic solvents; separation; extraction; purification; downstream process; computational chemistry; bioactive compounds
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Green chemistry, an essential pillar of sustainable development, seeks to minimize the environmental impact of chemical processes. Using eco-friendly solvents in separation and extraction processes offers a promising avenue for promoting sustainability in various industries. Green solvents, including ionic liquids, deep eutectic solvents, supercritical fluids, and bio-based solvents, offer several advantages compared to the traditional solvents of the present time. These solvents possess low toxicity, biodegradability, and reduced environmental impact, and can be sourced from abundant, renewable resources, further enhancing their sustainability, rendering them highly desirable for separation, extraction and purification processes. Through careful fine-tuning of their composition and physicochemical properties, these solvents can be tailored to achieve efficient and selective extraction/purification of target compounds. Moreover, recent advances in green solvents often contribute to improved energy efficiency, reduced waste production, and the potential for developing novel products with unique characteristics. Thus, green solvents applied in extraction and separation processes can actively promote sustainable development, reduce environmental pollution and support the transition to a greener future.

Contributions to this Special Issue should cover trends and advances in industrial biotechnology, including the area of separation, extraction and purification processes using green solvents. The extraction of bioproducts as enzymes, biosurfactants, biopesticides, bioplastics, etc., from different media is also included and welcome. We invite our colleagues to submit their original contributions—be it research manuscripts, short communications, or reviews—to this Special Issue. We believe that a comprehensive collection of the latest knowledge in this field will foster new connections among researchers and inspire innovative ideas for the sustainable development of extraction processes.

This Special Issue focuses on the following two topics located within the scope of Processes: separation processes and sustainable processes.

Prof. Dr. Maria Alice Zarur Coelho
Dr. Filipe Smith Buarque
Guest Editors

Manuscript Submission Information

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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Processes is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • green chemistry
  • green solvent
  • extraction
  • separation
  • purification
  • ionic liquids
  • deep eutectic solvents
  • bio-based solvent
  • supercritical solvent

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Published Papers (1 paper)

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Research

13 pages, 1658 KiB  
Article
The Effect of Agitation and the Use of Perfluorodecalin on Lipase Production by Yarrowia lipolytica in a Bioreactor
by Filipe Smith Buarque, Roseli Lopes da Silva, Ana Iraidy Santa Brígida, Priscilla Amaral and Maria Alice Zarur Coelho
Processes 2025, 13(3), 865; https://doi.org/10.3390/pr13030865 - 15 Mar 2025
Viewed by 435
Abstract
Lipase production by the strictly aerobic yeast Yarrowia lipolytica is closely related to the content of dissolved oxygen in the culture medium. Some strategies to improve oxygen transfer to microorganisms have already been used, such as the use of perfluorocarbons (PFCs). The present [...] Read more.
Lipase production by the strictly aerobic yeast Yarrowia lipolytica is closely related to the content of dissolved oxygen in the culture medium. Some strategies to improve oxygen transfer to microorganisms have already been used, such as the use of perfluorocarbons (PFCs). The present work investigates the influence of agitation speed and the use of perfluorodecalin (PFC) on the profile of the produced lipases. Lipase production increased 2.5-fold with a higher agitation speed (550 to 650 rpm) without PFCs in the medium. The presence of an oxygen carrier led to a significant 91% increase in lipase production at lower shaking speeds compared to the assay without PFC; however, an increase in lipase production was not detected with PFC at 650 rpm. The protein profiles exhibited typical bands for two lipases produced (near 40 and 60 kDa), and these bands became more intense when PFC was added during production, as a result of the large enhancement in lipolytic activity. Additionally, the protein profiles obtained from extracts at 650 rpm were clearer and more selective regardless of the presence of PFC, suggesting an enhancement in specific activity associated with increased shaking. These findings highlight the significant impact of oxygen availability on lipase production, offering valuable insights for industrial applications. Full article
(This article belongs to the Special Issue Green Solvent for Separation and Extraction Processes)
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