Dispersive Extraction Techniques: New Strategies and Applications

A special issue of Separations (ISSN 2297-8739). This special issue belongs to the section "Purification Technology".

Deadline for manuscript submissions: closed (10 March 2023) | Viewed by 1839

Special Issue Editor


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Guest Editor
Department of Analytical Chemistry, University of Valencia, 46100 Burjassot, Spain
Interests: microextraction; sample preparation; nanomaterials; chromatography
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Special Issue Information

Dear Colleagues,

Dispersive-based extraction techniques have attracted considerable attention in the sample preparation field in the last decade. The higher contact area between the extraction phase and the sample solution favours the mass transfer of analytes, improving kinetics and achieving good results in lower extraction times. Depending on the nature of the extraction phase, it can be solvent-based or sorbent-based, with either dispersive liquid–liquid microextraction (DLLME) or dispersive solid-phase extraction (DSPE), respectively, the two most widely used dispersive techniques.

The present Special Issue covers the recent advances, strategies, and applications of this type of extraction technique in different fields (e.g., bioclinical, environmental, pharmaceutical, cosmetics, food, etc.), as well as the use of novel (nano)materials and solvents, which offer great opportunities for the development of phases for more efficient and versatile approaches.

We hope that this Special Issue will provide an analytical perspective on the current research involved in the field of microextraction. Original articles and review articles by experts are particularly welcome.

Dr. Juan L. Benedé
Guest Editor

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Keywords

  • dispersive liquid–liquid microextraction
  • dispersive solid-phase extraction
  • matrix solid-phase dispersion
  • microextraction techniques
  • nanomaterials
  • biological applications
  • pharmaceutical and cosmetics
  • food analysis

Published Papers (1 paper)

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Research

14 pages, 872 KiB  
Article
Monitoring of Biogenic Amines in Human Urine Using Dispersive Liquid–Liquid Microextraction and Liquid Chromatography with High-Resolution Mass Spectrometry
by María Consolación Rodríguez-Palazón, Natalia Arroyo-Manzanares, Natalia Campillo and Pilar Viñas
Separations 2023, 10(4), 232; https://doi.org/10.3390/separations10040232 - 29 Mar 2023
Cited by 2 | Viewed by 1245
Abstract
The biogenic amines (BAs) synephrine (SNP), phenylephrine (PEP), tyramine (TYR), and octopamine (OCT) may be present in products widely consumed for weight loss, muscle power, and in energy supplements. Considering the toxicity of these BAs at high levels and their biomarker role in [...] Read more.
The biogenic amines (BAs) synephrine (SNP), phenylephrine (PEP), tyramine (TYR), and octopamine (OCT) may be present in products widely consumed for weight loss, muscle power, and in energy supplements. Considering the toxicity of these BAs at high levels and their biomarker role in some human pathologies, their monitoring in urine can be of great help in the detection of abusive consumption or disease. In this work, a combination of dispersive liquid–liquid microextraction (DLLME) with ultra-high performance liquid chromatography and quadrupole time-of-flight mass spectrometry (UHPLC-Q-TOF-MS) for the simultaneous determination of four aromatic BAs in human urine is presented. The sample treatment included a previous derivatization step with dansyl chloride to achieve the highest extraction efficiency in the DLLME procedure for which a mixture of 350 μL of chloroform and 2 mL of ethanol was added to 5 mL of derivatized urine. Limits of detection were in the 0.54–3.6 µg L−1 range. Method precision and trueness were estimated at two concentration levels and were in the 3.4–10.2% and 93.6–114% ranges, respectively. The analysis of nine urine samples showed concentration levels for TYR between 52 and 304 µg L−1. Non-targeted analysis of the samples was undertaken to control the presence of other BAs and related metabolites, and none of these species was detected. Full article
(This article belongs to the Special Issue Dispersive Extraction Techniques: New Strategies and Applications)
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