Analysis and Bioanalysis of Pharmaceuticals: Sample Preparation and Chromatography
A special issue of Separations (ISSN 2297-8739). This special issue belongs to the section "Chromatographic Separations".
Deadline for manuscript submissions: 10 November 2024 | Viewed by 7852
Special Issue Editors
Interests: pharmaceutical analysis; bioanalysis of medicines and drugs of abuse; chromatography; spectrophotometry; methods validation; medicines stability studies; quality control of pharmaceutical products and dietary supplements
Interests: analytical testing of medicines; drugs of abuse; natural products; bioanalytical methods; chromatography (HPLTC, GC-MS, HPLC, LC-MS); spectrophotometry; food safety; environmental toxicology
Interests: pharmaceutical analysis; biopharmacy; pharmaceutical industry; chromatography; spectrophotometry; methods validation; medicines stability
Interests: extraction and chemical profiling of bioactive compounds from vegetal matters; emerging contaminant residue analysis in environmental and biological matrices; food safety; analytical investigations; HPLC, LC-HRMS/MS; method validation
Special Issue Information
Dear Colleagues,
It is widely recognized that pharmaceutical analysis plays a pivotal role not only in the quality control of pharmaceutical products but also in the development of original or generic formulations. Simultaneously, pharmaceutical bioanalysis stands out as an indispensable tool in pharmacokinetic and therapeutic drug monitoring studies. In both pharmaceutical analysis and bioanalysis, chromatography is a predominant analytical technique that has been widely practiced for decades.
Innovative breakthroughs, including ultra-performance thin-layer chromatography (HPTLC), ultra-high-pressure liquid chromatography (UHPLC), and hyphenated techniques like gas chromatography–mass spectrometry (GC-MS) and liquid chromatography–mass spectrometry (LC–MS) or two-dimensional liquid chromatography (2D-LC), chiral separations, core–shell columns, and novel stationary phases, have collectively improved chromatography, permitting faster speed, higher resolution, greater sensitivity, and increased precision.
Unquestionably, sample preparation also constitutes a critical facet of the analytical process. Recent advances introduced by the development of novel technologies and sorbents have substantially enhanced the performance of sample preparation techniques.
This Special Issue is dedicated to original research publications applying optimized extraction techniques to molecules of significant biopharmaceutical interest from various matrices and their quantification using chromatographic techniques coupled with sensitive detectors. Moreover, the scope extends to review papers that present an exhaustive examination of the state of the art in chromatographic analysis and bioanalysis concerning specific active pharmaceutical ingredients.
Dr. Anne Marie Ciobanu
Prof. Dr. Daniela Baconi
Prof. Dr. George Traian Alexandru Burcea-Dragomiroiu
Dr. Carmen Lidia Chitescu
Guest Editors
Manuscript Submission Information
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Keywords
- chromatography
- drug analysis
- sample preparation
- method validation
- biological matrices
- extraction
- liquid chromatography
- gas chromatography
- pharmaceuticals
- sample preparation
- high-performance thin-layer chromatography
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