Pharmaceuticals in the Aquatic Environment: Monitoring, Impacts and Ecological Risk

A special issue of Toxics (ISSN 2305-6304). This special issue belongs to the section "Emerging Contaminants".

Deadline for manuscript submissions: 15 August 2024 | Viewed by 789

Special Issue Editor


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Guest Editor
Institute of Biomedical Sciences Abel Salazar and Interdisciplinary Centre for Marine and Environmental Research, University of Porto, Porto, Portugal
Interests: pharmaceuticals; endocrine disruptors; PAHs; pesticides; PCBs; industrial pollutants; risk assessment
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Pharmaceuticals are essential for human and animal health. However, after their use, these compounds are generally rapidly excreted, mainly in faeces and urine, as water-soluble metabolites. These often reach wastewater treatment plants (WWTPs), where, in addition to not being eradicated, some become active compounds with harmful effects on aquatic species and ecosystems. Moreover, unused pharmaceuticals can cause a severe risk if they reach the environment due to improper disposal.

Ultimately, parental compounds or their metabolites may affect humans and domestic animals via drinking water and the ingestion of its byproducts in meat, animal feed, and dairy plant crops, among others. This aspect may cause undesirable health issues for humans and animals.

In this Special Issue, we aim to collate studies referring to the environmental presence and impact of pharmaceuticals, such as hormones, antibiotics, antidepressants, anti-inflammatories and analgesics, beta-blockers, and anticancer medications, ideally offering a global panorama of the contamination of aquatic abiotic and biotic matrices and its impacts on both animal and human health.

Dr. Maria João Rocha
Guest Editor

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Keywords

  • pharmaceuticals
  • aquatic environment
  • endocrine disruptors
  • risk assessment
  • infertility
  • cancer

Published Papers (1 paper)

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29 pages, 1627 KiB  
Review
Non-Steroidal Anti-Inflammatory Drugs in the Aquatic Environment and Bivalves: The State of the Art
by Pedro Pires, André M. P. T. Pereira, Angelina Pena and Liliana J. G. Silva
Toxics 2024, 12(6), 415; https://doi.org/10.3390/toxics12060415 - 5 Jun 2024
Viewed by 363
Abstract
In recent years, contaminants of emerging concern have been reported in several environmental matrices due to advances in analytical methodologies. These anthropogenic micropollutants are detected at residual levels, representing an ecotoxicological threat to aquatic ecosystems. In particular, the pharmacotherapeutic group of non-steroidal anti-inflammatories [...] Read more.
In recent years, contaminants of emerging concern have been reported in several environmental matrices due to advances in analytical methodologies. These anthropogenic micropollutants are detected at residual levels, representing an ecotoxicological threat to aquatic ecosystems. In particular, the pharmacotherapeutic group of non-steroidal anti-inflammatories (NSAIDs) is one of the most prescribed and used, as well as one of the most frequently detected in the aquatic environment. Bivalves have several benefits as a foodstuff, and also as an environment bioindicator species. Therefore, they are regarded as an ideal tool to assess this issue from both ecotoxicological and food safety perspectives. Thus, the control of these residues in bivalves is extremely important to safeguard environmental health, also ensuring food safety and public health. This paper aims to review NSAIDs in bivalves, observing their consumption, physicochemical characteristics, and mechanisms of action; their environmental occurrence in the aquatic environment and aquatic biota; and their effects on the ecosystem and the existent legal framework. A review of the analytical methodologies for the determination of NSAIDs in bivalves is also presented. Full article
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