Nephrotoxicity Induced by Drugs and Chemicals in the Environment

A special issue of Toxics (ISSN 2305-6304). This special issue belongs to the section "Human Toxicology and Epidemiology".

Deadline for manuscript submissions: 30 June 2024 | Viewed by 133

Special Issue Editors


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Guest Editor
Department of Pharmacology, Physiology and Toxicology, Joan C. Edwards School of Medicine, Marshall University, One John Marshall Drive, Huntington, WV 25755, USA
Interests: nephrotoxicity mechanisms; renal bioactivation of toxicants; structure-toxicity relationships
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
Department of Biomedical Sciences, Joan C. Edwards School of Medicine, Marshall University, Huntington, WV 25755, USA
Interests: nephrotoxicity; hepatotoxicity; cancer chemotherapy drugs; acetaminophen; fungicides; solvents; oxidative stress; 4-hydroxynonenal; proximal tubule; protein carbonylation
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The kidney is an organ with multiple functions. Kidneys are important for maintaining water and electrolyte balance and the excretion of endogenous and exogenous compounds. In addition, kidneys perform multiple essential endocrine functions. Unfortunately, the kidney is the target for toxicity induced by a wide range of chemicals or their metabolites, including drugs, pesticides, industrial chemicals, natural products, and environmental pollutants. Being a rapidly perfused organ, the kidney is exposed to significant amounts of blood-borne toxicants, which can induce toxicity to the kidney through many different mechanisms. Identifying potential nephrotoxic chemicals and understanding safe and nephrotoxic levels of those chemicals, their mechanisms of toxicity, and potential measures to reduce their toxic effects is critical to reducing the harmful effects of these agents on renal function in humans and other organisms.

This Special Issue will provide recent advances in understanding the nephrotoxic properties and mechanisms of toxicity induced by drugs and non-therapeutic chemicals, including environmental pollutants and natural products. Knowledge continues to be generated about known nephrotoxicants as well as newly identified chemical threats to the kidney from made-made and natural sources. This issue will contribute recent findings to advance the field of renal toxicology.

Prof. Dr. Gary O. Rankin
Prof. Dr. Monica Valentovic
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Toxics is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • kidney
  • nephrotoxicity
  • drugs
  • environmental pollutants
  • metals
  • halogenated hydrocarbons
  • pesticides

Published Papers

This special issue is now open for submission.
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