Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
3.4
4.6
Journals
Toxics
Special Issues
Organic Endocrine Disrupters: From Quantification to Risk Assessment
share announcement

Organic Endocrine Disrupters: From Quantification to Risk Assessment

A special issue of Toxics (ISSN 2305-6304). This special issue belongs to the section "Emerging Contaminants".

Deadline for manuscript submissions: 18 August 2024 | Viewed by 1827

Special Issue Editors

Dr. Lidia Caporossi

E-Mail Website
Guest Editor
Department of Occupational and Environmental Medicine, Epidemiology and Hygiene, INAIL-National Institute for Insurance against Accidents at Work, 00078 Monteporzio Catone, Italy
Interests: occupational and environmental exposure to chemicals; clinical toxicology; endocrine disrupters; reprotoxicity; biological monitoring
Special Issues, Collections and Topics in MDPI journals
Prof. Dr. Maria Marino

E-Mail Website
Guest Editor
Dipartimento di Scienze, Università Roma Tre, Rome, Italy
Interests: endocrine disrupters; phthalate; alkylphenols; BPA; organohalogenates; environmental monitoring; biological monitoring; reprotoxicity; thyroid; metabolic effects
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Among the chemicals able to interact with the endocrine system, organic substances represent a certain risk due to their widespread use in industrial processes, particularly in the production of everyday commercial products.

These substances mainly belong to the chemical families of phthalates, alkylphenols, organohalogenates, organic solvents. Human exposure to such substances could occur from food contamination, dermal absorption or inhalation. However, both occupational and non-occupational exposure have been identified via a parenteral route in case of specific medical treatment.

We are pleased to invite you to contribute to this Special Issue, in order to highlight all possible adverse health effects that could occur after this type of chemical exposure. In fact, the majority of research about the toxicity of organic endocrine disruptors focuses on reprotoxicity, both for men and women; however, recent evidence calls for more studies to underline the possible adverse health effects on the thyroid gland and glucose metabolism (with particular attention to the onset of type II diabetes, insulin resistance, and obesity).

This Special Issue aims to present new analytical approaches for the environmental and biological monitoring of these chemicals, contributions that clarify the mechanisms of biochemical interaction between these substances and the human body, epidemiological studies to underline different possible diseases and proposals for risk assessment and management in specific environments (such as occupational areas).

In this Special Issue, original research articles and reviews are welcome. Research areas may include (but are not limited to) the following: analytical chemistry, toxicology, and epidemiology.

We look forward to receiving your contributions.

Dr. Lidia Caporossi
Prof. Dr. Maria Marino
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Toxics is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • endocrine disrupters
  • phthalate
  • alkylphenols
  • BPA
  • organohalogenates
  • environmental monitoring
  • biological monitoring
  • reprotoxicity
  • thyroid
  • metabolic effects

Published Papers (1 paper)

Order results
Result details
Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:

Research

9 pages, 743 KiB  
Communication
Rapid Assessment of Di(2-ethylhexyl) Phthalate Migration from Consumer PVC Products
by Jiwon An, Hyun-Ho Roh, Haeyoon Jeong, Kuen-Yong Lee and Taiyoun Rhim
Toxics 2024, 12(1), 7; https://doi.org/10.3390/toxics12010007 - 20 Dec 2023
Viewed by 1363
Abstract
Poly(vinyl chloride) (PVC) is widely used to produce various consumer goods, including food packaging, toys for children, building materials, and cosmetic products. However, despite their widespread use, phthalate plasticizers have been identified as endocrine disruptors, which cause adverse health effects, thus leading to [...] Read more.
Poly(vinyl chloride) (PVC) is widely used to produce various consumer goods, including food packaging, toys for children, building materials, and cosmetic products. However, despite their widespread use, phthalate plasticizers have been identified as endocrine disruptors, which cause adverse health effects, thus leading to increasing concerns regarding their migration from PVC products to the environment. This study proposed a method for rapidly measuring the migration of phthalates, particularly di(2-ethylhexyl) phthalate (DEHP), from PVC products to commonly encountered liquids. The release of DEHP under various conditions, including exposure to aqueous and organic solvents, different temperatures, and household microwaves, was investigated. The amount of DEHP released from both laboratory-produced PVC films and commercially available PVC products was measured to elucidate the potential risks associated with its real-world applications. Furthermore, tests were performed to evaluate cytotoxicity using estrogen-dependent and -independent cancer cell lines. The results revealed a dose-dependent impact on estrogen-dependent cells, thus emphasizing the potential health implications of phthalate release. This comprehensive study provides valuable insights into the migration patterns of DEHP from PVC products and forms a basis for further research on the safety of PVC and plasticizers. Full article
(This article belongs to the Special Issue Organic Endocrine Disrupters: From Quantification to Risk Assessment)
►▼ Show Figures

Figure 1

Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:
 
Displaying articles 1-1
Back to TopTop