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Veterinary Sciences
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Exploring Antimicrobial Strategies in Veterinary Medicine: From In Vitro Research...
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Exploring Antimicrobial Strategies in Veterinary Medicine: From In Vitro Research to In Vivo Applications

A special issue of Veterinary Sciences (ISSN 2306-7381). This special issue belongs to the section "Veterinary Physiology, Pharmacology, and Toxicology".

Deadline for manuscript submissions: 30 June 2026 | Viewed by 2192

Special Issue Editors

Dr. Manuela Oliveira

E-Mail Website
Guest Editor
1. Centre for Interdisciplinary Research in Animal Health (CIISA), Faculty of Veterinary Medicine, University of Lisbon, 1300-477 Lisboa, Portugal
2. Associate Laboratory for Animal and Veterinary Sciences (AL4AnimalS), 1300-477 Lisboa, Portugal
3. Centre for Ecology, Evolution and Environmental Changes (cE3c) & Global Change and Sustainability Institute (CHANGE), Faculty of Sciences, University of Lisbon, Campo Grande, 1749-016 Lisboa, Portugal
Interests: one health; clinical bacteriology; biofilms; antimicrobial resistance; wildlife bacteriology; mycology; bacterial virulence; genomics; infections pathogenesis; food safety
Special Issues, Collections and Topics in MDPI journals
Dr. Eva Cunha

E-Mail Website
Guest Editor
1. Centre for Interdisciplinary Research in Animal Health (CIISA), Faculty of Veterinary Medicine, University of Lisbon, 1300-477 Lisboa, Portugal
2. Associate Laboratory for Animal and Veterinary Sciences (AL4AnimalS), 1300-477 Lisboa, Portugal
Interests: antimicrobial compounds; antimicrobial resistance; bacterial virulence; biofilms; veterinary medicine; infectious diseases
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Antimicrobial resistance (AMR) represents a significant threat to global health, as it reduces the effectiveness of antimicrobials, leads to difficult-to-treat infections, and increases pressure on healthcare systems. This issue extends beyond human health, influencing the animal and environmental sectors. In Veterinary Medicine, AMR is responsible for the failure of standard treatments, increased animal suffering and higher mortality and morbidity rates, and poses a significant threat to public health due to the potential spread of resistant pathogens between animals and humans. Therefore, international organizations such as the WHO, WOAH, and FAO have developed multiple strategies to tackle this health problem. Strategies to control AMR dissemination include the research and development of antimicrobial strategies, including the investigation of new drugs and diagnostic methods, the enhancement of disinfection protocols and the application of biocides, and the study of known antimicrobial compounds and their repurposing for greater efficacy. Ongoing research in these fields holds the potential to revolutionize the management of infectious diseases in animals, ensuring better health outcomes and safeguarding public health through the responsible utilization of antimicrobial agents.

Dr. Manuela Oliveira
Dr. Eva Cunha
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Veterinary Sciences is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2100 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • antimicrobial resistance (AMR)
  • one health
  • infections
  • veterinary medicine
  • pathogens
  • antimicrobial agents

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Published Papers (2 papers)

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Research

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13 pages, 297 KB  
Article
Quaternary Ammonium Biocide Resistance in Non-Typhoidal Salmonella from Pig Carcasses
by Lorina Lourenço, Vanessa Ferreira da Silva, Madalena Vieira-Pinto, Manuela Oliveira and João B. Cota
Vet. Sci. 2026, 13(3), 247; https://doi.org/10.3390/vetsci13030247 - 5 Mar 2026
Viewed by 403
Abstract
Non-typhoidal Salmonella (NTS) are one of the most common foodborne pathogens worldwide, and pork is a major food vehicle together with eggs and poultry meat. Contamination of pork within food processing facilities, such as slaughterhouses, can be associated with persistence of Salmonella in [...] Read more.
Non-typhoidal Salmonella (NTS) are one of the most common foodborne pathogens worldwide, and pork is a major food vehicle together with eggs and poultry meat. Contamination of pork within food processing facilities, such as slaughterhouses, can be associated with persistence of Salmonella in the environment due to biocide resistance. In this study, we assessed the susceptibility of NTS isolates from pig carcasses to a QAC-based commercial formulation according to the EN 1656/2009 standard and the presence of QAC resistance genes through PCR. The qacEΔ1 and qacF genes were found in 31.8% and 29.5% of the isolates respectively, while qacE was absent. All isolates were found to be susceptible at a tested concentration 10 times lower (0.1%) than the minimum in-use recommended concentration, with MIC values below 0.1% (≈70 mg/L of Benzalkonium Chloride). Our findings point towards the importance of correct cleaning and disinfection protocols and the role of good hygiene practices as corrective and/or preventive measures to avoid cross-contamination. Full article
(This article belongs to the Special Issue Exploring Antimicrobial Strategies in Veterinary Medicine: From In Vitro Research to In Vivo Applications)

Review

Jump to: Research

41 pages, 5958 KB  
Review
Avian Candidiasis: A Comprehensive Review of Pathogenesis, Diagnosis, and Control
by Michelyne Haroun, Christophe Tratrat, Roshmon Thomas Mathew, Muhammad Munir, Muhammad Naeem Sattar, Mohamed Shawky, Hafedh Kochkar, Ouda Nasser Aldakhilallah, Abdul Ghafoor, Khalid G. Biro Turk, Athina Geronikaki and Hesham S. Ghazzawy
Vet. Sci. 2026, 13(2), 171; https://doi.org/10.3390/vetsci13020171 - 9 Feb 2026
Cited by 1 | Viewed by 1080
Abstract
This review is a comprehensive investigation of avian candidiasis, mainly caused by Candida albicans, although the prevalence of non-albicans Candida species has increased in domestic and wild birds. Avian candidiasis causes significant economic losses in poultry production through increased mortality, cost of [...] Read more.
This review is a comprehensive investigation of avian candidiasis, mainly caused by Candida albicans, although the prevalence of non-albicans Candida species has increased in domestic and wild birds. Avian candidiasis causes significant economic losses in poultry production through increased mortality, cost of treatments, and reduced growth rates, particularly in young birds and intensive farming operations. The pathogenesis section provides a description of the molecular virulence factors such as adhesin-mediated attachment (ALS, Agglutinin-Like Sequence family; HWP1, Hyphal Wall Protein 1), yeast-to-hypha morphogenesis, tissue damage by Candidalysin, biofilm formation on mucosal and abiotic surfaces, and secreted hydrolytic enzymes including secreted aspartyl proteinases (SAPs) and phospholipases. The identified predisposing factors include immunosuppression, malnutrition, abuse of antibiotics, bad husbandry, and crop stasis. The diagnostic methods discussed encompass cytological analysis and fungal culture on selective media to more sophisticated methods of molecular analysis (PCR, MALDI-TOF MS, and NGS). Antifungal susceptibility investigations indicate that nystatin and amphotericin B are still very effective against most avian isolates and that resistance to the azoles is on the rise, especially with respect to the non-albicans Candida species. Nystatin is still the first-line treatment of localized infections; azoles are still used for resistant or systemic infections despite their hepatotoxicity. Sanitation, proper nutrition, and proper use of antimicrobials are essential to prevent diseases. The knowledge gaps comprise the absence of avian-specific pharmacokinetic information, poor knowledge of species-species virulence phenotypes, and the lack of point-of-care diagnostics. The need to have integrated One Health surveillance systems is emphasized by the zoonotic potential of the avian Candida reservoirs. Full article
(This article belongs to the Special Issue Exploring Antimicrobial Strategies in Veterinary Medicine: From In Vitro Research to In Vivo Applications)
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