Immunity to Enteric Viruses
A special issue of Viruses (ISSN 1999-4915). This special issue belongs to the section "Viral Immunology, Vaccines, and Antivirals".
Deadline for manuscript submissions: closed (30 September 2024) | Viewed by 1591
Special Issue Editors
Interests: norovirus; rotavirus; viral and Clostridioides difficile diarrhea; gastroenteritic; vaccine efficacy evaluation; therapeutic nanobodies and IgY
Interests: human and animal rotavirus; norovirus and coronavirus; Llama derived-nanobodies; avian IgY; statistical validation of assays and animal models
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Enteric virus infections pose a significant global health challenge, particularly impacting infants and young children. This diverse group of viruses, including rotaviruses, noroviruses, sapoviruses, astroviruses, enteric adenoviruses and viruses in the Picobirnaviridae family are common etiological agents of acute viral gastroenteritis. The pathophysiology of viral diarrhea is multifaceted and complex, with various mechanisms at play. However, a crucial aspect of combatting these infections is the host's immune response, as well as the passive maternal immunity transferred thourgh the placenta to the baby’s bloodstream, and breast feeding acting locally in the neonatal gut. Both innate and adaptive immune mechanisms play pivotal roles in safeguarding the host against enteric viral infections, specially at the gut mucosa. In addition, maternal immunity can modulate this neonatal active immunity. Furthermore, variations in the host's genetic makeup and epigenetic, including differences in the expression of histo-blood group antigens and gut microbiota, are linked to susceptibility or resistance to specific enteric viruses. Research in this area has unveiled new avenues for potential interventions and therapies.
In this context, we are pleased to announce our Special Issue of Viruses, which aims to provide a comprehensive exploration of host immunity to these pathogens. We invite researchers to contribute their findings and insights through the submission of research articles, review articles and short communications. Topics of interest encompass innate and adaptive immune responses to enteric viruses, host genetic factors influencing susceptibility and the role of gut microbiota in immune defense. This Special Issue seeks to advance our understanding of how the host combats enteric viral infections, ultimately contributing to the development of more effective preventive and therapeutic measures.
Prof. Dr. Lijuan Yuan
Dr. Viviana Parreño
Guest Editors
Manuscript Submission Information
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Keywords
- rotavirus, norovirus, sapoviruses, astroviruses, enteric adenoviruses, picobirnaviruses
- intrinsic, innate, T cell and B cell responses to enteric viral infections
- immunity against enteric viruses
- gut microbiome and immunity to enteric viruses
- host genetic factors in immunity to enteric viruses
- passive maternal antibodies adquired through active transference
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