Search Results (283)

We propose Phase-Adaptive Federated Learning (PAFL), a novel framework for privacy-preserving personalized travel itinerary generation that dynamically balances privacy and utility through a phase-dependent aggregation mechanism inspired by phase-change materials. (1) PAFL’s primary objective is to dynamically optimize the privacy–utility trade-off in federated travel recommendation systems through phase-adaptive anonymization. The phase parameter φ ∈ [0, 1] operates as a tunable control variable that continuously adjusts the latent space geometry between differentially private (φ→1) and utility-optimized (φ→0) representations via a thermodynamic-inspired transformation. Conventional federated learning approaches often rely on static privacy-preserving techniques, which either degrade recommendation quality or inadequately protect sensitive user data; PAFL addresses this limitation through three key innovations: a latent-space phase transformer, a differential privacy-gradient inverter with mathematically provable reconstruction bounds (εt ≤ 1.0), and a lightweight sequential transformer. (2) PAFL’s core innovation lies in its phase-adaptive mechanism that dynamically balances privacy preservation through differential privacy and utility maintenance via gradient inversion, governed by the tunable phase parameter φ. Experimental results demonstrate statistically significant improvements, with 18.7% higher HR@10 (p < 0.01) and 62% lower membership inference risk compared to state-of-the-art methods, while maintaining εtotal < 2.3 over 100 training rounds. The framework advances federated learning for sensitive recommendation tasks by establishing a new paradigm for adaptive privacy–utility optimization. Full article

This study focuses on the energy absorption and wearer comfort attributes of regular lattice structures fabricated by laser powder bed fusion from two elastomeric materials, namely TPU1301 and TPE300, for use in personal protective equipment (PPE). This study compares Body-Centered Cubic (BCC), Face-Centered Cubic (FCC) and Kelvin (KE) lattice structures with density varying from 0.15 to 0.25 g/cm³, cell size varying from 10 to 14 mm and feature size varying from 1 to 3 mm. Quasi-static and dynamic compression testing confirmed that among the studied geometries, KE structures printed with TPE300 powders provide the best combination of reduced peak acceleration and increased compliance, thereby improving both safety and comfort. Using the protection–comfort maps built on the basis of this study enables the design of lightweight and compact protective structures. For example, if a safety layer protecting a 100 mm² surface area can be manufactured from either TPE300 or TPU1100 powders using either KE or FCC structures, the KE TPE300 layer will be 1.5 times thinner and 2.5 times lighter than its FCC TPU1301 equivalent. The results of this study thus provide a basis for the optimization of lattice structures in 3D-printed PPE to meet both service and manufacturing requirements. Full article

The blood–brain barrier (BBB) is a highly selective and natural protective membrane that restricts the entry of therapeutic agents into the central nervous system (CNS). This restrictive nature poses a major challenge for pharmacological treatment of a wide range of CNS disorders, including neurodegenerative disorders, brain tumors, and psychiatric conditions. Many chemical drugs and biopharmaceuticals are unable to cross the BBB, and conventional drug delivery methods often fail to achieve sufficient brain concentrations, leading to reduced therapeutic efficacy and increased risk of systemic toxicity. In recent years, targeted drug delivery strategies have emerged as promising approaches to overcome the BBB and enhance the delivery of therapeutic agents to the brain. Among these, receptor-mediated transcytosis (RMT) and transporter-mediated transcytosis (TMT) are two of the most extensively studied mechanisms for transporting drugs across brain endothelial cells into the brain parenchyma. Advances in materials science and nanotechnology have facilitated the development of multifunctional carriers with optimized properties, improving drug targeting, stability, and release profiles within the brain. This review summarizes the physiological structure of the BBB and highlights recent innovations in RMT- and TMT-mediated brain drug delivery systems, emphasizing their potential not only to overcome current challenges in CNS drug development, but also to pave the way for next-generation therapies that enable more precise, effective, and personalized treatment of brain-related diseases. Full article

This study aimed to evaluate the adverse effects of using Oxycide™ (Ecolab, Copenhagen, Denmark) disinfectant in dental practices and assess the need for improved safety measures. Materials and methods: An observational study was conducted in dental offices, evaluating 200 dental assistants exposed to Oxycide™ disinfectant. Data on disinfectant use practices, personal protective equipment, and reported symptoms were collected through an online questionnaire. Results: 63% (126 out of 200) of staff experienced symptoms including respiratory irritation, eye irritation, and skin reactions after Oxycide™ exposure. Inconsistent use of personal protective equipment and improper application techniques were observed. In conclusion, the use of Oxycide™ disinfectant in dental offices has been associated with a wide range of respiratory and cutaneous symptoms among staff, ranging from mild irritative manifestations to severe allergic reactions. Improved protocols, staff training, and consideration of safer alternatives are needed to protect dental personnel while maintaining infection control standards. For a sustainable dental practice, it is essential to balance effective disinfection with staff safety. While high-level disinfectants like Oxycide™ are effective against pathogens, their repeated use—especially in poorly ventilated areas—can lead to respiratory discomfort and skin reactions. To mitigate these risks, clear preventive measures should be implemented: adherence to manufacturer guidelines, proper ventilation, consistent use of personal protective equipment, and ongoing staff training. These steps are crucial to reducing exposure to irritants and ensuring a safe and efficient working environment. Full article

Concussion is a costly healthcare issue affecting sports, industry, and the defense sector. The financial impacts, however, extend beyond acute medical expenses, affecting an individual’s physical and cognitive abilities, as well as increasing the burden on coworkers, family members, and caregivers. More effective personal protective equipment may greatly reduce the risk of concussion and injury. Notably, aerogels are light, but traditionally fragile, non-Newtonian fluids, such as shear-thickening fluids, which generate more resistance when compressive force is applied. Herein, a composite material was developed by baking a shear-thickening fluid (i.e., starch) and combining it with a commercially available aerogel foam, thus maintaining a low cost. The samples were tested through the use of a ballistic pendulum system, using a spring-powered launcher and a gas-powered cannon, followed by ballistic penetration testing, using two electromagnetic accelerators and two different projectiles. During the cannon tests without a hardhat, the baked composite only registered 31 ± 2% of the deflection height observed for the pristine aerogel. The baked composite successfully protected the hygroelectric devices from coilgun projectiles, whereas the projectiles punctured the pristine aerogel. Leveraging the low-cost design of this new composite, personal protective equipment can be improved for various sporting, industrial, and defense applications. Full article

Thermal and moisture properties of the textile materials worn in close contact with the skin greatly contribute to the comfort of the workwear and of the personal protective clothing (PPC) assemblies they are part of. This study examines in depth the thermoregulatory properties of eighteen knitted fabrics used in polo shirts and T-shirts, which function as thermal underwear, standard workwear compliant with various regulations, or as base layers in PPC systems. Most of the fabrics specifically engineered for heat protection demonstrated superior air permeability (ranging from 700 to 1200 mm/s) and efficient moisture management (OMMC 0.5–0.7). Their drying time varied between 12 and 18 min, comparable to most commodity fibre blend fabrics investigated. Generally, the heat-protective fabrics were heavier and exhibited greater thermal and vapour resistance. However, despite minor variations in predicted thermal comfort, seventeen of the fabrics were classified in the same cluster. These findings offer valuable insights into the thermal and moisture management properties of knitted fabrics with various levels of protection, and the correlations found between their thermoregulatory and physical properties, such as mass and thickness, provide guidance for the development of innovative knitted materials for workwear that enhance wearer comfort. Full article

Skin is the largest organ of the human body and holds the functions of sensing, protecting, and regulating. Since ancient times, people have decorated their skin by painting themselves, cutting, and using accessories to express their personality and aesthetic consciousness as a kind of artistic expression, one that shows the development and change of aesthetic consciousness. However, there are concerns regarding the inconvenience, high time cost, and negative body perception with traditional tattoos. In addition, the trend of skin decoration has gradually withdrawn due to a lack of intelligent interaction. In response to these problems, we proposed a wearable electronic skin tattoo that offers a novel means of communication and emotional expression for individuals with communication impairments, WABEIT. The tattoo uses skin-friendly PDMS as the base material, combines multi-mode sensing components such as silver wire circuit, a programmable Surface-Mounted Device (SMD), a thin-film-pressure sensor, and a heart rate sensor, and combines the embedded development board Arduino Nano for intelligent interaction, forming a wearable electronic interactive tattoo capable of sensing the environment, human–computer interaction, and the changeable performance of intelligent perception. The sensor is also equipped with a mobile power supply to support portability. The advantages of WABEIT are as follows: first, it avoids the pain, allergy, and long production process of traditional tattoos. Second, the patterns can adapt to different needs and generate feedback for users, which can effectively express personal emotions. Thirdly, the facility of removal reduces social discrimination and occupational constraints, which is especially suitable for East Asia. Experimental results indicate that the device exhibits a high sensitivity in signal response, a wide variety of pattern changes, and reliable interactive capabilities. The study demonstrates that the proposed design philosophy and implementation strategy can be generalized to the interactive design of other wearable devices, thereby providing novel insights and methodologies for human–computer interaction, electronic devices, and sensor applications. Full article

With the increasing demand for environmental protection, flattened bamboo is gradually attracting attention as a sustainable material. The purpose of this study was to compare and analyze the surface properties of flattened bamboo and PU self-foaming plastic by subjective and objective evaluation methods, and to explore the substitutability of flattened bamboo and PU self-foaming plastic in furniture design. Objective test methods such as surface hardness testing, gloss measurement, and friction coefficient determination were used in the experiments, and the subjective evaluation of visual and tactile perception of the materials were combined with the semantic differential method. It was found that the flattened bamboo was generally superior to the PU self-foaming plastics in terms of color, gloss, roughness, and wettability, giving a more delicate, warm and comfortable feeling, while the PU self-foaming plastics stood out in terms of personalized style. Further correlation analysis showed that surface gloss and color saturation had a significant effect on the users’ psychological feelings. This study provides a scientific basis for replacing PU self-foaming plastic with bamboo in furniture design and also provides a valuable reference for “bamboo instead of plastic” product design. Full article

Objective: Working physical activity, physical fitness and energy intake were studied for their effect on all-cause mortality and age at death in residential cohorts followed-up for 61 years. Material and Methods: There were two residential cohorts of middle-aged men examined in 1960 with a total of 1712 subjects, and three indexes were measured, i.e., physical activity by a questionnaire (three classes—sedentary, moderate, vigorous: Phyac), physical fitness, estimated by combining arm circumference, heart rate, and vital capacity by Principal Component Analysis, whose score was divided into three tertile classes (low, intermediate, and high: Fitscore), and energy intake in Kcalories, estimated by dietary history divided into three tertile classes (low, intermediate, high: Calories), plus five traditional cardiovascular risk factors (age, cigarette smoking, body mass index, systolic blood pressure, and serum cholesterol). Cox models were used to predict all-cause mortality as a function of those adjusted indexes. Multiple linear regression models were used to predict age at death as a function of the same co-variates and a larger number of them. At the 61-year follow-up, 1708 men had died. Results: There were large correlations across the three indexes. Prediction of all-cause mortality showed the independent and complementary roles of the three indexes to all be statistically significant and all protective for their highest levels. However, the Fitness score outperformed the role of Phyac, while the role of Calories was unexpectedly strong. The same outcome was found when predicting age at death, even in the presence of 25 covariates representing risk factors, personal characteristics, and prevalent major diseases. Conclusions: Working physical activity, a score of physical fitness and energy intake, seems directly related to lower all-cause mortality and to higher age at death, thus suggesting a large part of independence. Full article

The COVID-19 pandemic exposed critical gaps in healthcare infrastructure, particularly the lack of effective isolation anterooms for managing infectious diseases. This study presents TrainerWall, a cost-effective, portable anteroom designed for rapid deployment in both high-resource and resource-limited settings. TrainerWall features a modular, self-supporting structure with antimicrobial materials, integrated sanitization, and adaptable dimensions, ensuring seamless integration into healthcare environments without disrupting operations. Its dual function as an infection control measure and a training platform makes it particularly valuable for non-specialized healthcare workers. Pre-clinical evaluations conducted in simulated hospital environments have demonstrated their ease of deployment, procedural efficiency, and positive impact on infection control practices, particularly in non-specialized departments. Designed for quick assembly, disassembly, and transport, TrainerWall enhances healthcare readiness during outbreaks, offering a scalable solution where permanent infrastructure is lacking. Future integration of augmented reality and interactive guidance could further improve training and compliance. This innovation provides an accessible, adaptable approach to infection control, particularly in underserved regions and emergency response scenarios. Full article

Ballistic impact protection has been enhanced through the use of advanced materials, such as shear thickening fluids (STFs) and auxetic structures. These materials provide high energy absorption, flexibility, and comfort, offering promising solutions for the development of lightweight and effective personal protective equipment. The combination of STFs and auxetic structures has been shown to optimize impact resistance while maintaining mobility. To validate this, a composite made of an auxetic structure impregnated with a polyurethane and STF mixture was evaluated for energy absorption. The auxetic structure, fabricated using high-tenacity polyester, demonstrated superior energy absorption compared to standard foams. The impregnation of the auxetic structure with 200 and 400 wt% Biresin and STF mixtures significantly enhanced its impact energy absorption capacity up to 76% compared to the auxetic reference. With the addition of the STF at a 25:75 ratio into the biresin matrix, improvements were also verified in the absorption, up to 7%, due to the non-Newtonian behavior of the STF, demonstrating the potential of these composites for low-impact applications. Full article

This essay examines relationships between adoptees and the (extended) adoptive family, focusing on the inheritance rights of adopted persons as entry points into levels and cycles of their belonging and un-belonging. The essay contextualizes a case report (or summary reports) on the kind of estrangement in the adoptee world that is fueled by inheritance disputes. It delves into postadoption perceptions and thus into the “unwritten” truths about adoption and its possible fallout. It draws from archival sources, semi-structured interviews (life-story interviewing), and life writing by adoptees, and also from a sequence of real-life exchanges dating back to 2018. All these sources focus on the contested inheritance of children, now older adults, who were adopted from Greece in the 1950s–60s and who became (or should have become) subsequent heirs to the estates of their adoptive parents and/or relatives. The Greek out-of-country adoptions of the postwar and early Cold War era involved more than 4000 children, most of whom were sent to the United States. The various testimonies and sections reflect critically on the continuing trend to infantilize the adopted persons, forever the adopted children, to push their origins back into the past and into geographical distance, to untie the family connections they have forged over the course of half a century. The examples take the reader from the adoptive family’s pre-adoption attempts at disowning the child through the postadoption stage of the end of an adopted lifetime, including cases of the extended adoptive family’s attempts at “de-adopting” the adopted person. This essay includes various sources of life-cycle documentation, among them an extensive case study and online obituaries. It adheres to truth and authenticity by incorporating fairly long original quotations, which, in the case study of the second half especially, assist the reader in comprehending much historical information in a question-and-answer format. This bolder structure offers the advantage of taking the reader step by step through the transactions of a prominent Greek adoption scheme (Rebecca and Maurice Issachar) and also through the various layers of the postadoption mindset and minefield. The material presented here is intended to raise awareness that change can and must still benefit the Greek adoptees today, whose lives may have been permeated by conditionality and nonlinearity. I conclude that, in the cases discussed here, the child’s orphanhood may well be a perpetual state, with the adoptee being orphaned of individuality and of a protective family on more than just one occasion. Full article

Background. Despite dentistry’s alarmingly high energy use, plastic waste, and travel emissions, research on Romanian dental students’ sustainability awareness is absent. This study aimed to assess their knowledge of the environmental impact of dental materials and practices, hypothesizing that early exposure to sustainability education would benefit preclinical students most. Materials and Methods. A cross-sectional survey using a form questionnaire with 15 items was conducted on 1800 dental students at Carol Davila University of Medicine and Pharmacy, Bucharest, Romania, for one week in March 2022. The questionnaire, consisting of socio-demographics, students’ perspectives on sustainability in dentistry, and personal sustainability, was analyzed using SPSS 26. Data analysis included the Shapiro–Wilk test for normality, Fisher’s exact test for categorical variables, the Mann–Whitney U test for non-parametric quantitative comparisons, and Z-tests with Bonferroni correction for contingency tables. Results. A response rate of 26.06% was achieved, with 469 participants. The majority (51.1%), particularly males (66.1%), perceived sustainability as promoting durability. The most common definition of sustainability (33.8%) was related to environmental protection, with significantly higher agreement among female students (39.4%) (p = 0.001). While 49.3% of participants identified single-use plastics in patient care as having the greatest environmental impact in dental practices, 39.2% of female students, primarily from clinical study years (50%), ranked patient paperwork and records as the most significant factor (p = 0.031). The highest-carbon-footprint dental procedures were considered to be amalgam and composite fillings (50.7%), with clinical year students indicating this as the most relevant issue (62.8% vs. 47.7%) (p = 0.011). Students aged 25–30 were more actively engaged in sustainability initiatives compared to the younger group (p = 0.005), while all students over 30 identified scaling and polishing as the most impactful procedure (p < 0.001). A majority of students supported future university sustainability initiatives (62.7%) and an elective course on sustainability in dentistry (65%). Female students showed significantly greater interest than male students in both initiatives (66.3% vs. 52.7%, p = 0.003 and 70.8% vs. 49.6%, p < 0.001, respectively). Conclusions. Greater awareness of sustainability was found in preclinical-year dental students and among female students, with knowledge gaps in clinical-year students, particularly regarding the environmental impact of dental practices and materials. Introducing sustainability courses could better prepare future dentists for sustainable practices in dentistry. Research collaborations and curriculum reforms to further promote sustainability would also be beneficial. Full article

This study focuses on reducing the weight of oxygen respirators in firefighters’ personal protective equipment (PPE), which currently accounts for about 56% of the total weight. The heavy PPE, weighing between 20 and 25 kg, restricts movement and can lead to musculoskeletal injuries. To address this, the study investigates using a carbon fiber-reinforced composite for the backrest of the oxygen respirator to reduce weight while maintaining strength. The backrest was fabricated using a long-fiber thermoplastic (LFT) composite made with PA66 resin and 30wt.% carbon fiber content. Initially, the injection-molding process conditions were identified to achieve a tensile strength of 85 MPa or higher. Additionally, flame retardants were added to improve fire resistance, with AF-480 at 5 wt.% found to be the best option. Subsequently, optimal injection conditions were set by fabricating the back rest with the composite by applying the Taguchi method to satisfy the required tensile strength. As a result, the composite material achieved a 12.8% weight reduction while maintaining the required strength. This development is expected to significantly improve firefighter safety, leading to more effective firefighting and reduced human and property damage. Full article

Background: Personal Protective Equipment supply chains encountered severe shortages during the 2020 COVID-19 pandemic. Many manufacturers are located in China, the first country that issued lockdowns, and Personal Protective Equipment inventories, managed by the Just in Time policy, were unprepared for such a demand surge. The existing literature examines the impacts of COVID-19 on the global Personal Protective Equipment supply chain. However, five years after the onset of COVID-19, there is still a lack of studies focusing on Personal Protective Equipment supply chain behavior in Italy. Italy is a particularly significant case study, as it was the first Western country to be severely impacted by the pandemic. This work develops an empirical analysis to answer the following research questions. How did the main variables in the Italian Personal Protective Equipment supply chain change during the early stages of the pandemic? How can we explain such changes? Methods: A questionnaire survey was carried out among producers, importers, and distributors of Personal Protective Equipment operating in Italy. The responses to the questionnaire were analyzed by applying both descriptive statistics and the Kruskal–Wallis test. Results: The findings indicate that importers and distributors experienced more significant increases in orders than producers after the first lockdown, due to the new manufacturer’s setup period before full-scale operations. Conclusions: The study might encourage examinations of how material management strategies aimed at reducing inventory can impact situations involving unanticipated increases in demand. Moreover, it offers insights into the causes and consequences of the criticalities faced by the Italian Personal Protective Equipment supply chain during the first pandemic phases, contributing to creating knowledge that might be useful to define strategies to enhance supply chain resilience. Full article