Table of Contents
Toxins, Volume 9, Issue 9 (September 2017)
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Cover Story (view full-size image) Apicomplexans are pathogenic protozoan parasites that cause a wide range of diseases, including [...] Read more. Apicomplexans are pathogenic protozoan parasites that cause a wide range of diseases, including malaria and toxoplasmosis, in a variety of host organisms. These intracellular parasites employ pore-forming proteins to disrupt host cell membranes to entirely traverse host cells or to egress from the parasite-containing vacuole during the complex life cycle. Recently solved three-dimensional structures of various apicomplexan pore-forming proteins have shed light on the distinct mechanisms that are utilized at various steps in the parasitic life cycle. View this paper