Next Article in Journal
Isoform Sequencing Provides a More Comprehensive View of the Panax ginseng Transcriptome
Previous Article in Journal
The Chloroplast Genome Sequence of Scutellaria baicalensis Provides Insight into Intraspecific and Interspecific Chloroplast Genome Diversity in Scutellaria
Article Menu
Issue 9 (September) cover image

Export Article

Open AccessArticle
Genes 2017, 8(9), 225; doi:10.3390/genes8090225

Identification of the Ovine Keratin-Associated Protein 26-1 Gene and Its Association with Variation in Wool Traits

1
Gansu Key Laboratory of Herbivorous Animal Biotechnology, Faculty of Animal Science and Technology, Gansu Agricultural University, Lanzhou 730070, China
2
International Wool Research Institute, Gansu Agricultural University, Lanzhou 730070, China
3
Gene-marker Laboratory, Faculty of Agricultural and Life Sciences, Lincoln University, Lincoln 7647, New Zealand
*
Authors to whom correspondence should be addressed.
Received: 11 July 2017 / Revised: 1 September 2017 / Accepted: 6 September 2017 / Published: 13 September 2017
(This article belongs to the Special Issue Complex Genetic Loci)
View Full-Text   |   Download PDF [1317 KB, uploaded 13 September 2017]   |  

Abstract

Keratin-associated proteins (KAPs) are structural components of wool and hair fibres, and are believed to play a role in defining the physico-mechanical properties of the wool fibre. In this study, the putative ovine homologue of the human KAP26-1 gene (KRTAP26-1) was sequenced and four variants (named A–D) were identified. The sequences shared some identity with each other and with other KRTAPs, but they had the greatest similarity with the human KRTAP26-1 sequence. This suggests they represent different variants of ovine KRTAP26-1. The association of these KRTAP26-1 variants with wool traits was investigated in the 383 Merino-Southdown cross sheep. The presence of B was associated (p < 0.05) with an increase in mean fibre diameter (MFD), mean fibre curvature, and prickle factor (PF). The presence of C was found to be associated (p < 0.05) with an increase in wool yield (Yield) and mean staple length (MSL), and a decrease in MFD, fibre diameter standard deviation (FDSD), and PF. The results suggest that sheep with C have, on average, higher wool quality. These results may be useful in the future development of breeding programs based on decreasing wool MFD and FDSD, or on increasing wool MSL. View Full-Text
Keywords: keratin-associated protein KAP26-1 gene (KRTAP26-1); variation; wool traits; sheep keratin-associated protein KAP26-1 gene (KRTAP26-1); variation; wool traits; sheep
Figures

Figure 1

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Li, S.; Zhou, H.; Gong, H.; Zhao, F.; Hu, J.; Luo, Y.; Hickford, J.G.H. Identification of the Ovine Keratin-Associated Protein 26-1 Gene and Its Association with Variation in Wool Traits. Genes 2017, 8, 225.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Genes EISSN 2073-4425 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top