Nanoparticle-Assisted Metabolomics
Abstract
:1. Introduction
2. Nanoparticles in Analytical Chemistry
3. Nanoparticles for Metabolomics Sample Preparation
3.1. Silica Nanoparticles for Protein Removal and Metabolite Extraction in Protein-Rich Biofluids
3.2. Nanoparticles for Solid-Phase Extraction for the Enrichment of Low Abundant Metabolites
4. Nanoparticle-Metabolite Interaction Assist Metabolite Detection
4.1. Silica Nanoparticles for NMR Spectra Simplification
4.2. Nanoparticles to Establish Intra-Molecular Correlations between NMR Signals
4.3. Nano-Scaled Surface Structure for Ionization Enhancement in Mass Spectrometry
5. Conclusions and Future Perspective
Acknowledgments
Author Contributions
Conflicts of Interest
References
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Zhang, B.; Xie, M.; Bruschweiler-Li, L.; Brüschweiler, R. Nanoparticle-Assisted Metabolomics. Metabolites 2018, 8, 21. https://doi.org/10.3390/metabo8010021
Zhang B, Xie M, Bruschweiler-Li L, Brüschweiler R. Nanoparticle-Assisted Metabolomics. Metabolites. 2018; 8(1):21. https://doi.org/10.3390/metabo8010021
Chicago/Turabian StyleZhang, Bo, Mouzhe Xie, Lei Bruschweiler-Li, and Rafael Brüschweiler. 2018. "Nanoparticle-Assisted Metabolomics" Metabolites 8, no. 1: 21. https://doi.org/10.3390/metabo8010021