Novel Antioxidant Mechanisms for Health and Diseases
A special issue of Antioxidants (ISSN 2076-3921). This special issue belongs to the section "Health Outcomes of Antioxidants and Oxidative Stress".
Deadline for manuscript submissions: 10 March 2025 | Viewed by 9443
Special Issue Editor
Special Issue Information
Dear Colleagues,
Antioxidant therapy effectively addresses oxidative-stress-related diseases. These conditions arise from the depletion of endogenous antioxidants, which leads to oxidative stress. Therefore, supplementation with exogenous antioxidants, including vitamins and polyphenols, has been suggested. However, some studies report potential drawbacks, such as neutralizing beneficial reactive oxygen species (ROS) or requiring excessive doses for effectiveness, making clinical application challenging. Oxidative stress plays a role in various contexts, from pathological conditions to fatigue and the side effects of anticancer drugs. Therefore, rapid and precise replenishment of antioxidants that specifically counteract harmful ROS is crucial.
Emerging approaches to antioxidant treatment offer new perspectives. Nutrigenomics-based treatments aim to enhance the body's antioxidant capacity by influencing gene expression through dietary choices. Nano-antioxidant therapy employs inorganic substances to continuously generate antioxidants within the body. There are also treatments that increase the production of antioxidants by regulating the microbiome. These treatments are innovative antioxidant therapies that differ from those used in the past, aiming to enhance the body's antioxidant capacity by modifying the internal environment. The objective of this Special Issue is to delve into these novel antioxidant treatments to gain a better understanding of the new mechanisms that regulate antioxidant activity in the body. We hope that this Special Issue will lead to the discovery of new antioxidant treatments for oxidative-stress-related diseases.
Dr. Yoshihisa Koyama
Guest Editor
Manuscript Submission Information
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Keywords
- antioxidant therapy
- reactive oxygen species
- oxidative stress
- nano-antioxidant therapy
- nutrigenomics
- microbiome
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