Mitochondrial Redox in Cardio-Metabolic Disease and Cardio-Oncology
A special issue of Antioxidants (ISSN 2076-3921). This special issue belongs to the section "Health Outcomes of Antioxidants and Oxidative Stress".
Deadline for manuscript submissions: closed (10 February 2022) | Viewed by 4502
Special Issue Editors
2. Hunter Medical Research Institute, New Lambton Heights, Australia
Interests: cardio-oncology; cardiometabolic; obesity; heart failure; redox stress; biomarkers; general cardiology
Special Issues, Collections and Topics in MDPI journals
2. Hunter Medical Research Institute, New Lambton Heights, Australia
Interests: cardio-oncology; cardiometabolic; obesity; heart failure; redox stress; biomarkers; vascular biology
Special Issues, Collections and Topics in MDPI journals
Interests: coronary atherosclerosis; inflammation and oxidative stress in the heart and blood vessel; Clinical trials
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Increased oxidative stress has emerged as a major mediator of pathophysiological processes in many cardiovascular disease states, as well as major cardiovascular risk factors including obesity, cardiometabolic syndrome, and diabetes. Cardio-oncology, a new subspecialty concerned with cardiovascular complications of cancer and cancer therapies, is an emerging and rapidly growing area clinical concern and expanding research direction. Oxidative stress has also been proposed to play an important role in some of the toxicities of anticancer therapies.
While cellular oxidases are known sources of reactive oxygen species, mitochondria has now been implicated as a major source of reactive oxygen species, especially in diabetes, obesity, and cardiovascular diseases. Furthermore, oxidative-stress-mediated mitochondrial dysfunction has emerged as a potential key mechanism behind a number of cardiovascular diseases. It has also been postulated to be the driver of anthracycline-mediated cardiotoxicity and involved in other cancer-therapy-associated cardiovascular toxicities.
We invite original research and review articles focusing on role of mitochondrial oxidative stress in the setting of cardiometabolic disease and cardio-oncology.
Dr. Aaron Sverdlov
Dr. Doan Ngo
Prof. Dr. Gemma Figtree
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
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Keywords
- Mitochondrial oxidative stress
- Cardiometabolic syndrome
- Cardio-oncology
- Oxidative posttranslational modifications of proteins
- Redox therapeutics in cardiovascular disease
- Biomarkers of cardiovascular oxidative stress