Functional Foods with Modulating Action on Metabolic Risk Factors: 2nd Edition

A special issue of Foods (ISSN 2304-8158). This special issue belongs to the section "Food Nutrition".

Deadline for manuscript submissions: 28 February 2025 | Viewed by 1579

Special Issue Editors


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Guest Editor

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Guest Editor
Department of Nutrition, Health Sciences Center, Federal University of Paraíba, João Pessoa 58051-900, Paraíba, Brazil
Interests: gut microbiota; probiotics; nutrition; arterial hypertension; metabolic disease; translational studies
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Special Issue Information

Dear Colleagues,

Volume I of this Special Issue (https://www.mdpi.com/journal/foods/special_issues/Functional_Foods_Metabolic) was a great success and has gained the attention and interest of many scholars. I take the opportunity here to thank them for their contributions and support. As the topic continues to gain the attention of scholars and play a pivotal role, we are looking forward to the launch of Volume II. I hope it will be as successful as Volume I and add significant value to the field.

Health-related metabolic risk factors, such as increased blood pressure, hyperglycemia, obesity and dyslipidemias, can lead to metabolic syndrome and enhanced risk of cardiovascular disease, stroke and death. In recent years, there has been increasing evidence of functional foods, food components and bioactive molecules of plant, animal and microbial origins exerting preventive and therapeutic benefits for human health by modulating the host metabolism, physiology, nutrition and immune functions. For this Special Issue of Foods, we are inviting the submission of manuscripts to present and compile the effects of traditional and emerging functional foods and food components on metabolic risk factors from a translational perspective by combining in vitro, ex vivo and animal studies, and or clinical trials/approaches. Original and unpublished research and highest-quality review papers addressing the physiology, cellular, genomics and molecular mechanisms underlying the modulating action of functional foods and food components in inflammation, dyslipidemias, blood pressure, oxidative stress, and immune and endocrine signaling pathways are encouraged.

Prof. Dr. Evandro Leite de Souza
Prof. Dr. José Luiz de Brito Alves
Guest Editors

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Keywords

  • plant foods
  • animal foods
  • microbial-origin foods
  • food components
  • dyslipidemias
  • type 2 diabetes mellitus
  • obesity
  • raised blood pressure
  • oxidative stress
  • inflammation

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Published Papers (1 paper)

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Review

30 pages, 2522 KiB  
Review
Targeting Gut Microbiota with Probiotics and Phenolic Compounds in the Treatment of Atherosclerosis: A Comprehensive Review
by José Patrocínio Ribeiro Cruz Neto, Micaelle Oliveira de Luna Freire, Deborah Emanuelle de Albuquerque Lemos, Rayanne Maira Felix Ribeiro Alves, Emmily Ferreira de Farias Cardoso, Camille de Moura Balarini, Hatice Duman, Sercan Karav, Evandro Leite de Souza and José Luiz de Brito Alves
Foods 2024, 13(18), 2886; https://doi.org/10.3390/foods13182886 - 12 Sep 2024
Viewed by 1182
Abstract
Atherosclerosis (AS) is a chronic inflammatory vascular disease. Dysregulated lipid metabolism, oxidative stress, and inflammation are the major mechanisms implicated in the development of AS. In addition, evidence suggests that gut dysbiosis plays an important role in atherogenesis, and modulation of the gut [...] Read more.
Atherosclerosis (AS) is a chronic inflammatory vascular disease. Dysregulated lipid metabolism, oxidative stress, and inflammation are the major mechanisms implicated in the development of AS. In addition, evidence suggests that gut dysbiosis plays an important role in atherogenesis, and modulation of the gut microbiota with probiotics and phenolic compounds has emerged as a promising strategy for preventing and treating AS. It has been shown that probiotics and phenolic compounds can improve atherosclerosis-related parameters by improving lipid profile, oxidative stress, and inflammation. In addition, these compounds may modulate the diversity and composition of the gut microbiota and improve atherosclerosis. The studies evaluated in the present review showed that probiotics and phenolic compounds, when consumed individually, improved atherosclerosis by modulating the gut microbiota in various ways, such as decreasing gut permeability, decreasing TMAO and LPS levels, altering alpha and beta diversity, and increasing fecal bile acid loss. However, no study was found that evaluated the combined use of probiotics and phenolic compounds to improve atherosclerosis. The available literature highlights the synergistic potential between phenolic compounds and probiotics to improve their health-promoting properties and functionalities. This review aims to summarize the available evidence on the individual effects of probiotics and phenolic compounds on AS, while providing insights into the potential benefits of nutraceutical approaches using probiotic strains, quercetin, and resveratrol as potential adjuvant therapies for AS treatment through modulation of the gut microbiota. Full article
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