Active Ingredients from Foods: Biochemical and Processing Aspects

A special issue of Foods (ISSN 2304-8158). This special issue belongs to the section "Food Physics and (Bio)Chemistry".

Deadline for manuscript submissions: closed (30 November 2020) | Viewed by 41981

Special Issue Editor


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Guest Editor
Department of Medical Biochemistry, Molecular Biology, and Immunology, School of Medicine, University of Seville, 41009 Seville, Spain
Interests: immunonutrition; novel foods; olive oil; lipid metabolism; protein hydrolysates; bioactive peptides; foodomics
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Special Issue Information

Dear Colleagues,

Nutritional biochemistry is one of the research lines that make up the nutritional sciences—a discipline that encompasses the knowledge of nutrients and other food components, with emphasis on their range of function and influence on mammalian physiology, health, and behavior. Nutritional biochemistry is a subdiscipline comprised of the core knowledge, concepts, and methodology related to the chemical properties of nutrients and other dietary constituents and to their biochemical, metabolic, physiological, and epigenetic functions. At present, new formulations for the production of functional foods, beverages, and animal feed with health benefits are on demand. In this Special Issue, we expect to gather interdisciplinary research about bioactive ingredients from foods, highlighting the potential for novel applications in the nutraceutical industry. This Special Issue is open to all contributions aimed at innovative and in-depth study of recovery from bioactive compounds and/or their pioneering applications.

Prof. Dr. Sergio Montserrat-de la Paz
Guest Editor

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Keywords

  • bioactive compounds
  • functional foods
  • nutraceutics
  • nutritional biochemistry
  • lipids
  • agro-food by-products
  • food waste

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Published Papers (8 papers)

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Editorial

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2 pages, 141 KiB  
Editorial
Active Ingredients from Foods: Biochemical and Processing Aspects
by Sergio Montserrat-de la Paz
Foods 2021, 10(6), 1240; https://doi.org/10.3390/foods10061240 - 29 May 2021
Cited by 1 | Viewed by 2063
Abstract
The global food and food technology market is in rapid growth [...] Full article
(This article belongs to the Special Issue Active Ingredients from Foods: Biochemical and Processing Aspects)

Research

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13 pages, 3416 KiB  
Article
Effect of Drum-Drying Conditions on the Content of Bioactive Compounds of Broccoli Pulp
by Constanza Córdova, Juan P. Vivanco, Julián Quintero and Andrea Mahn
Foods 2020, 9(9), 1224; https://doi.org/10.3390/foods9091224 - 2 Sep 2020
Cited by 10 | Viewed by 5280
Abstract
This work studied the effect of drum-rotation frequency, drum temperature, and water-to-pulp ratio in a double-drum drier on the content of sulforaphane, glucoraphanin, total phenolic compounds, ascorbic acid, and antioxidant activity of broccoli pulp through a multilevel factorial design with one replicate. Drum-drying [...] Read more.
This work studied the effect of drum-rotation frequency, drum temperature, and water-to-pulp ratio in a double-drum drier on the content of sulforaphane, glucoraphanin, total phenolic compounds, ascorbic acid, and antioxidant activity of broccoli pulp through a multilevel factorial design with one replicate. Drum-drying conditions did not significantly affect sulforaphane content, unlike glucoraphanin, however the poor adherence of broccoli pulp resulted in a final product with undefined shape and heterogeneous color. On the other hand, antioxidant activity was unevenly affected by drying conditions; however, drum-rotation frequency affected it in the same way that phenolic compounds and ascorbic acid, showing a concordant behavior. The ascorbic acid content decreased significantly after drying, and it was highly dependent on the experimental factors, resulting in a regression model that explained 90% of its variability. Drum-rotation frequency of 5 Hz, drum temperature of 125 °C, and water-to-pulp ratio of 0.25 resulted in an apparent increase of sulforaphane and phenolic compounds content of 13.7% and 47.6%, respectively. Drum drying has great potential to fabricate dehydrated broccoli-based foods with functional properties. Besides, since drum drying has low investment and operation costs, it represents a very attractive option for the industrialization of broccoli derivatives. Full article
(This article belongs to the Special Issue Active Ingredients from Foods: Biochemical and Processing Aspects)
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14 pages, 1327 KiB  
Article
New Liquid Source of Antioxidant Phenolic Compounds in the Olive Oil Industry: Alperujo Water
by María África Fernández-Prior, Juan Carlos Pérez Fatuarte, Alejandra Bermúdez Oria, Isabel Viera-Alcaide, Juan Fernández-Bolaños and Guillermo Rodríguez-Gutiérrez
Foods 2020, 9(7), 962; https://doi.org/10.3390/foods9070962 - 21 Jul 2020
Cited by 17 | Viewed by 3543
Abstract
The current management of alperujo as the main solid by-product from the two-phase olive oil extraction system has led to the appearance of a new liquid effluent that until now was treated together with the alperujo itself. The composition and antioxidant properties of [...] Read more.
The current management of alperujo as the main solid by-product from the two-phase olive oil extraction system has led to the appearance of a new liquid effluent that until now was treated together with the alperujo itself. The composition and antioxidant properties of its bioactive components at different depths of the pond were studied using colorimetric and HPLC with UV and MS detectors, DPPH, reducing power and rancimat. The concentration of suspended solids varied between 1.71 and 8.49 g/L, total fat was between 0.74 and 1.47 g/L, and total phenols were found between 3.74 and 4.11 g/L, which included hydroxytyrosol, 3,4-dihydroxyphenylglycol and tyrosol as the main phenols. Two types of extracts were obtained through two industrial systems with ethyl acetate and by chromotography, with an average content in total sugars of 2.1% and 3.16%, total phenols of 17.9% and 28.6% and hydroxytyrosol of 51.5 and 79.0 mg/g of extract, respectively. The activity presented by the chromatographic extract was higher in terms of free radical sequestering capacity, reducing power and the inhibition of lipid oxidation. Obtaining bioactive extracts would improve the formulation of food with natural components and at the same time would be the first step in a biorefinery to improve the management of the new effluent. Full article
(This article belongs to the Special Issue Active Ingredients from Foods: Biochemical and Processing Aspects)
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14 pages, 509 KiB  
Article
Fruit-Based Beverages Contain a Wide Range of Phytochemicals and Intervention Targets Should Account for the Individual Compounds Present and Their Availability
by Charles Bestwick, Lorraine Scobbie, Lesley Milne, Gary Duncan, Louise Cantlay and Wendy Russell
Foods 2020, 9(7), 891; https://doi.org/10.3390/foods9070891 - 7 Jul 2020
Cited by 13 | Viewed by 3887
Abstract
Benefits from micronutrients within fruit juice and smoothies are well documented, but fewer studies research the role of phytochemicals. Well-controlled human studies are essential to evaluate their impact, particularly on glucose and lipid regulation but also gastrointestinal health. Planning these studies requires data [...] Read more.
Benefits from micronutrients within fruit juice and smoothies are well documented, but fewer studies research the role of phytochemicals. Well-controlled human studies are essential to evaluate their impact, particularly on glucose and lipid regulation but also gastrointestinal health. Planning these studies requires data on the potential molecular targets. Here we report a comprehensive metabolomic (LC-MS) analysis of the phytochemical composition of four commonly consumed beverages, including data on whether they are free to be absorbed early in the gastrointestinal tract or bound to other plant components. Smoothies contained a wide range of phenolics (free and bound), whereas the fruit juices contained higher amounts of fewer compounds. Orange juice was rich in bound hesperidin (1.97 ± 0.39 mg/100 mL) and hydroxycinnamic acids, likely to be delivered to the colon with the potential to have an impact on gut health. Apple juice contained free chlorogenic acid (3.11 ± 1.03 mg/100 mL), phloridzin (0.40 ± 0.03 mg/100 mL), catechin (0.090 ± 0.005 mg/100 mL), and epicatechin (0.38 ± 0.02 mg/100 mL), suggesting potential roles in glucose uptake reduction or positive effects on systemic blood flow. Redox screening established that differences in chemical composition impacted on bioactivity, highlighting the importance of availability from the matrix. This suggests that fruit-based beverage interventions should target specific mechanisms depending on the fruits from which they are comprised and in particular, the availability of the individual constituents. Full article
(This article belongs to the Special Issue Active Ingredients from Foods: Biochemical and Processing Aspects)
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16 pages, 3370 KiB  
Article
Evaluation of Anti-Inflammatory and Atheroprotective Properties of Wheat Gluten Protein Hydrolysates in Primary Human Monocytes
by Sergio Montserrat-de la Paz, Noelia M. Rodriguez-Martin, Alvaro Villanueva, Justo Pedroche, Ivan Cruz-Chamorro, Francisco Millan and Maria C. Millan-Linares
Foods 2020, 9(7), 854; https://doi.org/10.3390/foods9070854 - 30 Jun 2020
Cited by 23 | Viewed by 3559
Abstract
Bioactive protein hydrolysates have been identified in several sources as possible agents in the prevention and treatment of many diseases. A wheat gluten (WG) concentrate was hydrolyzed by Alcalase under specific conditions. The resulting hydrolysates were evaluated by in vitro cell-free experiments leading [...] Read more.
Bioactive protein hydrolysates have been identified in several sources as possible agents in the prevention and treatment of many diseases. A wheat gluten (WG) concentrate was hydrolyzed by Alcalase under specific conditions. The resulting hydrolysates were evaluated by in vitro cell-free experiments leading to the identification of one bioactive WG protein hydrolysate (WGPH), which was used at 50 and 100 μg/mL on primary human monocytes. Reactive oxygen species (ROS) and nitrite levels and RT-qPCR and ELISA techniques were used to analyze the functional activity of WGPH. Our results showed that WGPH hydrolyzed in 45 min (WGPH45A) down-regulated gene expression of Interleukin (IL)-, IL-6, IL-17, and Interferon gamma (IFNγ) and reduced cytokine release in lipopolysaccharide (LPS)-stimulated monocytes. In addition, WGPH45A down-regulated gene-related to atherosclerotic onset. Our results suggest that WGPH45A has a potent anti-inflammatory and atheroprotective properties, reducing the expression of gene-related inflammation and atherosclerosis that could be instrumental in maintaining cardiovascular homeostasis. Full article
(This article belongs to the Special Issue Active Ingredients from Foods: Biochemical and Processing Aspects)
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14 pages, 2582 KiB  
Article
Emulsifying and Anti-Oxidative Properties of Proteins Extracted from Industrially Cold-Pressed Rapeseed Press-Cake
by Karolina Östbring, Kajsa Nilsson, Cecilia Ahlström, Anna Fridolfsson and Marilyn Rayner
Foods 2020, 9(5), 678; https://doi.org/10.3390/foods9050678 - 25 May 2020
Cited by 23 | Viewed by 4582
Abstract
One of the functional proteins in rapeseed—the amphiphilic protein oleosin—could be used to stabilize emulsions. The objectives of this study were to extract oleosins from cold-pressed rapeseed press-cake, optimize the extraction process, and investigate their emulsifying and anti-oxidative capacity. The proteins were recovered [...] Read more.
One of the functional proteins in rapeseed—the amphiphilic protein oleosin—could be used to stabilize emulsions. The objectives of this study were to extract oleosins from cold-pressed rapeseed press-cake, optimize the extraction process, and investigate their emulsifying and anti-oxidative capacity. The proteins were recovered from industrially cold-pressed rapeseed press-cake at different alkali pHs. Emulsifying properties and oxidation rates were assessed. Oleosin extracted at pH 9 stabilized smaller emulsion droplets than oleosin extracted at pH 12, although the protein yield was higher at pH 12. Emulsions were formulated from flaxseed oil and corn oil and were stabilized by oleosin, bovine serum albumin, de-oiled lecithin and Tween 20 h and the emulsions were stored in accelerated conditions (30 °C) for 12 days. Oleosin stabilized emulsions to the same extent as commercial food-grade emulsifiers. Flaxseed oil emulsions stabilized by oleosin had a significantly lower concentration of malondialdehyde (MDA) which indicates a lower oxidation rate compared to BSA, de-oiled lecithin and Tween 20. For corn oil emulsions, oleosin and BSA had a similar capacity to delay oxidation and were significantly more efficient compared to de-oiled lecithin and Tween 20. Rapeseed oleosin recovered from cold-pressed rapeseed press-cake could be a suitable natural emulsifier with anti-oxidation properties. Full article
(This article belongs to the Special Issue Active Ingredients from Foods: Biochemical and Processing Aspects)
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15 pages, 2036 KiB  
Article
Effects of Storage Conditions on Degradation of Chlorophyll and Emulsifying Capacity of Thylakoid Powders Produced by Different Drying Methods
by Karolina Östbring, Ingegerd Sjöholm, Marilyn Rayner and Charlotte Erlanson-Albertsson
Foods 2020, 9(5), 669; https://doi.org/10.3390/foods9050669 - 22 May 2020
Cited by 16 | Viewed by 4395
Abstract
Thylakoid membranes isolated from spinach have previously been shown to inhibit lipase/co-lipase and prolong satiety in vivo. There is a need to develop thylakoid products that not only have the desired characteristics and functionality after processing, but also are stable and provide equivalent [...] Read more.
Thylakoid membranes isolated from spinach have previously been shown to inhibit lipase/co-lipase and prolong satiety in vivo. There is a need to develop thylakoid products that not only have the desired characteristics and functionality after processing, but also are stable and provide equivalent effect on appetite over the promised shelf life. The aim of the present study was therefore to evaluate how the thylakoid powders’ characteristics and functionality were affected by moisture during storage. Thylakoids produced by drum-drying, spray-drying, and freeze-drying were incubated in controlled atmosphere with different relative humidity (10 RH%, 32 RH%, 48 RH% and 61 RH%) for 8 months. The water content in all powders was increased during storage. The water absorption was moisture-dependent, and the powders were considered hygroscopic. Relative humidity showed a definite influence on the rate of chlorophyll degradation and loss of green color in thylakoid powders after storage which correlated with impaired emulsifying capacity. Spray-dried powder had the overall highest chlorophyll content and emulsifying capacity at all RH-levels investigated. Spray drying was therefore considered the most suitable drying method yielding a powder with best-maintained functionality after storage. The results can be applied towards quality control of high-quality functional foods with appetite suppressing abilities. Full article
(This article belongs to the Special Issue Active Ingredients from Foods: Biochemical and Processing Aspects)
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Review

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20 pages, 1161 KiB  
Review
Grape (Vitis vinifera L.) Seed Oil: A Functional Food from the Winemaking Industry
by Maria E Martin, Elena Grao-Cruces, Maria C Millan-Linares and Sergio Montserrat-de la Paz
Foods 2020, 9(10), 1360; https://doi.org/10.3390/foods9101360 - 25 Sep 2020
Cited by 86 | Viewed by 13109
Abstract
Wine production is an ancient human activity that generates several by-products, which include some constituents known for their potential in health care and for their role in the food or cosmetic industries. Any variety of grape (Vitis vinifera L.) contains nutrients and [...] Read more.
Wine production is an ancient human activity that generates several by-products, which include some constituents known for their potential in health care and for their role in the food or cosmetic industries. Any variety of grape (Vitis vinifera L.) contains nutrients and bioactive compounds available from their juice or solid parts. Grape seed extract has demonstrated many activities in disease prevention, such as antioxidant effects, which make it a potential source of nutraceuticals. Grape seed is a remarkable winery industry by-product due to the bioactivity of its constituents. Methods for recovery of oil from grape seeds have evolved to improve both the quantity and quality of the yield. Both the lipophilic and hydrophilic chemicals present in the oil of V. vinifera L. make this wine by-product a source of natural nutraceuticals. Food and non-food industries are becoming novel targets of oil obtained from grape seeds given its various properties. This review focuses on the advantages of grape seed oil intake in our diet regarding its chemical composition in industries not related to wine production and the economic and environmental impact of oil production. Full article
(This article belongs to the Special Issue Active Ingredients from Foods: Biochemical and Processing Aspects)
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