Application of Brachytherapy in Clinical Practice (Volume II)

A special issue of Journal of Personalized Medicine (ISSN 2075-4426). This special issue belongs to the section "Clinical Medicine, Cell, and Organism Physiology".

Deadline for manuscript submissions: 10 August 2024 | Viewed by 980

Special Issue Editors


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Guest Editor
UOC Radioterapia Oncologica, Dipartimento di Diagnostica per Immagini, Radioterapia Oncologica ed Ematologia, Fondazione Policlinico Universitario A. Gemelli, IRCCS, 00168 Roma, Italy
Interests: interventional radiotherapy; brachytherapy; TPS algorithms; dosimetry; planning techniques
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Guest Editor
Fonaments Clinics Department, Faculty of Medicine, Universitat de Barcelon, Barcelona, Spain
Interests: interventional radiotherapy; brachytherapy techniques; gynecological oncology; educational gynecology
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Interventional radiotherapy (brachytherapy) started after the discovery of radium by Maria Slodowoska Curie, and, at present, has clear indications for treatment in almost tumour sites. The present Special Issue is one of the few publications dedicated to interventional radiotherapy in Europe.

The aim of this Special Issue is to present all the relevant clinical aspects of brachytherapy in all the tumour sites in a review or article format, considering future perspectives. To this end, clinical and medical brachytherapists work together with very specialised medical physicists, who are indispensable for the techniques’ evolution.

The submission of innovative clinical works in clinical practice and in physics, considering all the tumour sites is encouraged. Contributions exploring biological biomarkers and omics’ brachytherapy, as well Montecarlo aspects in vivo dosimetry, among others, are welcome.

We are soliciting reviews and original articles, and look forward to receiving your contributions.

Dr. Elisa Placidi
Dr. Àngeles Rovirosa
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Personalized Medicine is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • interventional radiotherapy
  • brachytherapy
  • medical brachytherapy
  • physics in brachytherapy
  • clinical applications
  • algorithms in interventional radiotherapy

Published Papers (1 paper)

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Research

15 pages, 6019 KiB  
Article
Characterization of Plastic Scintillator Detector for In Vivo Dosimetry in Gynecologic Brachytherapy
by Antonio Herreros, José Pérez-Calatayud, Facundo Ballester, Rosa Abellana, Joana Neves, Joana Melo, Luis Moutinho, Jordi Tarrats-Rosell, Sergi Serrano-Rueda, Luca Tagliaferri, Elisa Placidi and Angeles Rovirosa
J. Pers. Med. 2024, 14(3), 321; https://doi.org/10.3390/jpm14030321 - 20 Mar 2024
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Abstract
(1) Background: High dose gradients and manual steps in brachytherapy treatment procedures can lead to dose errors which make the use of in vivo dosimetry (IVD) highly recommended for verifying brachytherapy treatments. A new procedure was presented to obtain a calibration factor which [...] Read more.
(1) Background: High dose gradients and manual steps in brachytherapy treatment procedures can lead to dose errors which make the use of in vivo dosimetry (IVD) highly recommended for verifying brachytherapy treatments. A new procedure was presented to obtain a calibration factor which allows fast and robust calibration of plastic scintillation detector (PSD) probes for the geometry of a compact phantom using Monte Carlo simulations. Additionally, characterization of PSD energy, angular, and temperature dependences was performed. (2) Methods: PENELOPE/PenEasy code was used to obtain the calibration factor. To characterize the energy dependence of the PSD, the signal was measured at different radial and transversal distances. The sensitivity to the angular position was characterized in axial and azimuthal planes. (3) Results: The calibration factor obtained allows for an absorbed dose to water determination in full scatter conditions from ionization measured in a mini polymethylmethacrylate (PMMA) phantom. The energy dependence of the PSD along the radial distances obtained was (2.3 ± 2.1)% (k = 1). The azimuthal angular dependence measured was (2.6 ± 3.4)% (k = 1). The PSD response decreased by (0.19 ± 0.02)%/°C with increasing detector probe temperature. (4) Conclusions: The energy, angular, and temperature dependence of a PSD is compatible with IVD. Full article
(This article belongs to the Special Issue Application of Brachytherapy in Clinical Practice (Volume II))
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