Metabolism in Aquatic Products

A special issue of Metabolites (ISSN 2218-1989). This special issue belongs to the section "Animal Metabolism".

Deadline for manuscript submissions: 30 August 2024 | Viewed by 1192

Special Issue Editor


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Guest Editor
Department of Aquaculture, National Kaohsiung University of Science and Technology, Kaohsiung 81157, Taiwan
Interests: proteomics; metabolomics

Special Issue Information

Dear Colleagues,

Aquatic organisms, unlike terrestrial animals, are surrounded by an aquatic environment, which includes freshwater, brackish and seawater. In order to adapt to these diverse environments, aquatic organisms have evolved various adaptations, from external to internal physiological regulation.

Metabolism is a fundamental characteristic of life maintenance, so a special metabolic regulation will occur in the face of biotic or abiotic adaptation or external adversity stimulation. Because of the high biodiversity of aquatic organisms, different metabolic patterns of adaptation have evolved.

In recent years, due to global change, water pollution and other environmental factors, aquatic organisms have had to adapt to these stressors. Aquatic economic species, which also play an important role in global food supply, are under these pressures and often suffer from diseases or growth disorders that reduce production, directly affecting the supply of high-value proteins from fisheries.

Therefore, this Special issue aims to showcase research on the metabolism of aquatic organisms, especially recent research on the regulation of aquatic organisms’ metabolism using -omic approaches, which can give a broad and precise point of view on metabolism.

Prof. Dr. Kuohsun Chiu
Guest Editor

Manuscript Submission Information

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Keywords

  • metabolism
  • physiology
  • marine biology
  • fish
  • shellfish
  • nutrition
  • seafood
  • aquatic organism

Published Papers (1 paper)

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Research

27 pages, 5816 KiB  
Article
High Starch Induces Hematological Variations, Metabolic Changes, Oxidative Stress, Inflammatory Responses, and Histopathological Lesions in Largemouth Bass (Micropterus salmoides)
by Yuanyuan Xie, Xianping Shao, Penghui Zhang, Hao Zhang, Jiaxing Yu, Xinfeng Yao, Yifan Fu, Jiao Wei and Chenglong Wu
Metabolites 2024, 14(4), 236; https://doi.org/10.3390/metabo14040236 - 19 Apr 2024
Viewed by 533
Abstract
This study evaluated effects of high starch (20%) on hematological variations, glucose and lipid metabolism, antioxidant ability, inflammatory responses, and histopathological lesions in largemouth bass. Results showed hepatic crude lipid and triacylglycerol (TAG) contents were notably increased in fish fed high starch. High [...] Read more.
This study evaluated effects of high starch (20%) on hematological variations, glucose and lipid metabolism, antioxidant ability, inflammatory responses, and histopathological lesions in largemouth bass. Results showed hepatic crude lipid and triacylglycerol (TAG) contents were notably increased in fish fed high starch. High starch could increase counts of neutrophils, lymphocytes, monocytes, eosinophils, and basophils and serum contents of TAG, TBA, BUN, and LEP (p < 0.05). There were increasing trends in levels of GLUT2, glycolysis, gluconeogenesis, and LDH in fish fed high starch through the AKT/PI3K signal pathway. Meanwhile, high starch not only triggered TAG and cholesterol synthesis, but mediated cholesterol accumulation by reducing ABCG5, ABCG8, and NPC1L1. Significant increases in lipid droplets and vacuolization were also shown in hepatocytes of D3–D7 groups fed high starch. In addition, high starch could decrease levels of mitochondrial Trx2, TrxR2, and Prx3, while increasing ROS contents. Moreover, high starch could notably increase amounts of inflammatory factors (IL-1β, TNF-α, etc.) by activating NLRP3 inflammasome key molecules (GSDME, caspase 1, etc.). In conclusion, high starch could not only induce metabolic disorders via gluconeogenesis and accumulation of glycogen, TAG, and cholesterol, but could disturb redox homeostasis and cause inflammatory responses by activating the NLRP3 inflammasome in largemouth bass. Full article
(This article belongs to the Special Issue Metabolism in Aquatic Products)
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