Functional Sol-Gel Polymer-Based Materials

A special issue of Polymers (ISSN 2073-4360). This special issue belongs to the section "Polymer Networks".

Deadline for manuscript submissions: closed (29 February 2024) | Viewed by 894

Special Issue Editors


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Guest Editor
CICECO-Aveiro Institute of Materials, Department of Materials and Ceramic Engineering, University of Aveiro, Aveiro, Portugal
Interests: materials science; hybrid materials; sol-gel; biomaterialsglass

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Guest Editor
Aveiro Institute of Materials (CICECO), Department of Chemistry, University of Aveiro, 3810-193 Aveiro, Portugal
Interests: materials (polymers, ceramics, composites) for biomedical applications; drug delivery nanosystems; metallodrugs with antitumoral, antidiabetic, and antibacterial properties
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
CICECO-Aveiro Institute of Materials, University of Aveiro, Aveiro, Portugal
Interests: organic‒inorganic hybrid; carbon dots; photoluminescence; optoelectronic device
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Any type of specially designed material with a determined function can be defined as a functional material. Hybrid materials are a good example of functional materials, with applications in a variety of fields, such as electronics, photonics, medical or surface treatment. 

Historically, the First European Workshop on Hybrid Organic–Inorganic Materials, which took place in France in 1993, was probably the kick-off for the dizzying development in this area over the last 30 years, bringing us applications in such diverse areas. 

This Special Edition of MDPI Polymers, “Functional Sol–Gel-Based Materials”, is an invitation to all those who develop hybrid materials using the sol–gel method in different areas of applications to present and disseminate the most recent developments. 

Dr. José Carlos Almeida
Dr. Bárbara Leite Ferreira
Prof. Dr. Lianshe Fu
Guest Editors

Manuscript Submission Information

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Published Papers (1 paper)

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17 pages, 5011 KiB  
Article
Resveratrol-Loaded Polydimethylsiloxane–Silica Hybrid Materials: Synthesis, Characterization, and Antitumoral Activity
by Sofia Viegas, Diogo Marinheiro, Verónica Bastos, Ana L. Daniel-da-Silva, Ricardo Vieira, Helena Oliveira, José Carlos Almeida and Bárbara J. M. L. Ferreira
Polymers 2024, 16(7), 879; https://doi.org/10.3390/polym16070879 - 22 Mar 2024
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Abstract
In this work, hybrid materials within the polydimethylsiloxane–silica (PDMS–SiO2) system, synthesized via the sol–gel method, were developed and characterized for their potential to incorporate and release the bioactive compound resveratrol (RES). RES was incorporated into the materials with a high loading [...] Read more.
In this work, hybrid materials within the polydimethylsiloxane–silica (PDMS–SiO2) system, synthesized via the sol–gel method, were developed and characterized for their potential to incorporate and release the bioactive compound resveratrol (RES). RES was incorporated into the materials with a high loading efficiency (>75%) using the rotary evaporator technique. This incorporation induced the amorphization of RES, resulting in enhanced solubility and in vitro release when compared to the free polyphenolic compound. The release profiles displayed pH dependence, exhibiting notably faster release at pH 5.2 compared to pH 7.4. The gradual release of RES over time demonstrated an initial time lag of approximately 4 h, being well described by the Weibull model. In vitro cytotoxicity studies were conducted on human osteosarcoma cells (MG-63), revealing a concentration-dependent decrease in cell viability for RES-loaded samples (for concentrations >50 µg mL−1). Full article
(This article belongs to the Special Issue Functional Sol-Gel Polymer-Based Materials)
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