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Ultra-Sensitive Chem/Bio Sensors

A special issue of Sensors (ISSN 1424-8220). This special issue belongs to the section "Biosensors".

Deadline for manuscript submissions: closed (30 April 2021) | Viewed by 9300

Special Issue Editor

Dr. Oh Seok Kwon

E-Mail Website
Guest Editor
Infectious Disease Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Yuseong-gu, Daejeon 34141, Korea
Interests: chem/bio sensors; interfacing chemistry; nanomaterials; electronics; smart sensors
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Researchers are constantly developing new sensing technologies, aiming to obtain high-performance optical, physical, chemical, and biological sensors with ultra-sensitivity and selectivity. This has led to various detection techniques, including electrochemical and optical methods, field-effect transistors, lateral flow assay, etc. This Special Issue welcomes papers describing attractive and creative approaches for ultra-sensitive sensors. Topics of interest include: i) Sensing transistors, ii) Chemical and biological receptors, iii) Engineering of interfacial chemistry, and iv) Design of sensing platforms. In addition, smart sensing systems such as IoT (internet of things) and wireless systems are of interest because they enable to enhance devices’ sensing properties. Lastly, among industrial approaches, articles reporting on applications using ultra-sensitive sensors, such as healthcare monitoring, hazardous monitoring, and point-of-care tests, are also welcomed.

Dr. Oh Seok Kwon
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Sensors is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Chemical sensors
  • Biosensors
  • Interfacing chemistry
  • Enhanced sensing system (protocols)
  • Advanced sensing platforms
  • Point-of-care tests
  • Electronics

Published Papers (3 papers)

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Research

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20 pages, 3129 KiB  
Article
A Real-Time Thermal Sensor System for Quantifying the Inhibitory Effect of Antimicrobial Peptides on Bacterial Adhesion and Biofilm Formation
by Tobias Wieland, Julia Assmann, Astrid Bethe, Christian Fidelak, Helena Gmoser, Traute Janßen, Krishan Kotthaus, Antina Lübke-Becker, Lothar H. Wieler and Gerald A. Urban
Sensors 2021, 21(8), 2771; https://doi.org/10.3390/s21082771 - 14 Apr 2021
Cited by 11 | Viewed by 2980
Abstract
The increasing rate of antimicrobial resistance (AMR) in pathogenic bacteria is a global threat to human and veterinary medicine. Beyond antibiotics, antimicrobial peptides (AMPs) might be an alternative to inhibit the growth of bacteria, including AMR pathogens, on different surfaces. Biofilm formation, which [...] Read more.
The increasing rate of antimicrobial resistance (AMR) in pathogenic bacteria is a global threat to human and veterinary medicine. Beyond antibiotics, antimicrobial peptides (AMPs) might be an alternative to inhibit the growth of bacteria, including AMR pathogens, on different surfaces. Biofilm formation, which starts out as bacterial adhesion, poses additional challenges for antibiotics targeting bacterial cells. The objective of this study was to establish a real-time method for the monitoring of the inhibition of (a) bacterial adhesion to a defined substrate and (b) biofilm formation by AMPs using an innovative thermal sensor. We provide evidence that the thermal sensor enables continuous monitoring of the effect of two potent AMPs, protamine and OH-CATH-30, on surface colonization of bovine mastitis-associated Escherichia (E.) coli and Staphylococcus (S.) aureus. The bacteria were grown under static conditions on the surface of the sensor membrane, on which temperature oscillations generated by a heater structure were detected by an amorphous germanium thermistor. Bacterial adhesion, which was confirmed by white light interferometry, caused a detectable amplitude change and phase shift. To our knowledge, the thermal measurement system has never been used to assess the effect of AMPs on bacterial adhesion in real time before. The system could be used to screen and evaluate bacterial adhesion inhibition of both known and novel AMPs. Full article
(This article belongs to the Special Issue Ultra-Sensitive Chem/Bio Sensors)
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10 pages, 12030 KiB  
Article
Evaporation-Rate Control of Water Droplets on Flexible Transparent Heater for Sensor Application
by Jaesoung Park, Suhan Lee, Dong-Ik Kim, Young-You Kim, Samsoo Kim, Han-Jung Kim and Yoonkap Kim
Sensors 2019, 19(22), 4918; https://doi.org/10.3390/s19224918 - 12 Nov 2019
Cited by 8 | Viewed by 2988
Abstract
To develop high-performance de- or anti-frosting/icing devices based on transparent heaters, it is necessary to study the evaporation-rate control of droplets on heater surfaces. However, almost no research has been done on the evaporation-rate control of liquid droplets on transparent heaters. In this [...] Read more.
To develop high-performance de- or anti-frosting/icing devices based on transparent heaters, it is necessary to study the evaporation-rate control of droplets on heater surfaces. However, almost no research has been done on the evaporation-rate control of liquid droplets on transparent heaters. In this study, we investigate the evaporation characteristics of water droplets on transparent heater surfaces and determine that they depend upon the surface wettability, by modifying which, the complete evaporation time can be controlled. In addition, we study the defrosting and deicing performances through the surface wettability, by placing the flexible transparent heater on a webcam. The obtained results can be used as fundamental data for the transparent defrosting and deicing systems of closed-circuit television (CCTV) camera lenses, smart windows, vehicle backup cameras, aircraft windows, and sensor applications. Full article
(This article belongs to the Special Issue Ultra-Sensitive Chem/Bio Sensors)
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10 pages, 3099 KiB  
Letter
UV Irradiation-Induced SERS Enhancement in Randomly Distributed Au Nanostructures
by Dong-Jin Lee and Dae Yu Kim
Sensors 2020, 20(14), 3842; https://doi.org/10.3390/s20143842 - 09 Jul 2020
Cited by 3 | Viewed by 2783
Abstract
Currently used platforms for surface-enhanced Raman scattering (SERS) sensors generally employ metallic nanostructures for enrichment of the plasmonic hotspots in order to provide higher Raman signals, but this procedure is still considered challenging for analyte–surface affinity. This study reports a UV irradiation-induced SERS [...] Read more.
Currently used platforms for surface-enhanced Raman scattering (SERS) sensors generally employ metallic nanostructures for enrichment of the plasmonic hotspots in order to provide higher Raman signals, but this procedure is still considered challenging for analyte–surface affinity. This study reports a UV irradiation-induced SERS enhancement that amplifies the interactions between the analytes and metallic surfaces. The UV light can play critical roles in the surface cleaning to improve the SERS signal by removing the impurities from the surfaces and the formation of the negatively charged adsorbed oxygen species on the Au surfaces to enhance the analyte–surface affinity. To evaluate this scenario, we prepared randomly distributed Au nanostructures via thermal annealing with a sputtered Au thin film. The UV light of central wavelength 254 nm was then irradiated on the Au nanostructures for 60 min. The SERS efficiency of the Au nanostructures was subsequently evaluated using rhodamine 6G molecules as the representative Raman probe material. The Raman signal of the Au nanostructures after UV treatment was enhanced by up to approximately 68.7% compared to that of those that did not receive the UV treatment. We expect that the proposed method has the potential to be applied to SERS enhancement with various plasmonic platforms. Full article
(This article belongs to the Special Issue Ultra-Sensitive Chem/Bio Sensors)
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