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Polymers
Special Issues
The Diagnostics Based on Polymers
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The Diagnostics Based on Polymers

A special issue of Polymers (ISSN 2073-4360). This special issue belongs to the section "Polymer Applications".

Deadline for manuscript submissions: closed (15 March 2021) | Viewed by 8617

Special Issue Editor

Dr. Oh Seok Kwon

E-Mail Website
Guest Editor
Korea Research Institutes for Bioscience and Biotechnology, Daejeon 305-806, Republic of Korea
Interests: conductive nanomaterials; interfacing chemistry; optical nanomaterials; electronics; chem/bio sensors; optical sensors; point-of-care test
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Recently, various new-generation materials based on polymers been devised for application in different fields such as energy, envitronmental, medical and bio-applications. In particular, polymers can be designed as functional materials for diagnostics in vivo and in vitro, with special characteristics such as optical, electrical, and physical properties. In addition, there are also high-performance diagnostic platforms based on polymers, including point-of-care tests (PoCTs), lapid kits, bioimaging, BioMEMS, and so on. In this Special Issue, we invite research papers focusing on diagnostics based on polymers, including materials, instruments, methodologies, and so on, including but not limited to:

- Functional polymer materials;

- Interfacing polymer materials;

- Multidentate polymer materials;

- Polymer-based PoCTs;

- Polymer-based instruments.

Dr. Oh Seok Kwon
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Polymers is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Functional polymer materials
  • Interfacing polymer materials
  • Multidentate polymer materials
  • Polymer-based PoCTs
  • Polymer-based instruments

Published Papers (2 papers)

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Research

10 pages, 3422 KiB  
Article
Conductive GelMA–Collagen–AgNW Blended Hydrogel for Smart Actuator
by Jang Ho Ha, Jae Hyun Lim, Ji Woon Kim, Hyeon-Yeol Cho, Seok Geun Jo, Seung Hyun Lee, Jae Young Eom, Jong Min Lee and Bong Geun Chung
Polymers 2021, 13(8), 1217; https://doi.org/10.3390/polym13081217 - 09 Apr 2021
Cited by 13 | Viewed by 3813
Abstract
Blended hydrogels play an important role in enhancing the properties (e.g., mechanical properties and conductivity) of hydrogels. In this study, we generated a conductive blended hydrogel, which was achieved by mixing gelatin methacrylate (GelMA) with collagen, and silver nanowire (AgNW). The ratio of [...] Read more.
Blended hydrogels play an important role in enhancing the properties (e.g., mechanical properties and conductivity) of hydrogels. In this study, we generated a conductive blended hydrogel, which was achieved by mixing gelatin methacrylate (GelMA) with collagen, and silver nanowire (AgNW). The ratio of GelMA, collagen and AgNW was optimized and was subsequently gelated by ultraviolet light (UV) and heat. The scanning electron microscope (SEM) image of the conductive blended hydrogels showed that collagen and AgNW were present in the GelMA hydrogel. Additionally, rheological analysis indicated that the mechanical properties of the conductive GelMA–collagen–AgNW blended hydrogels improved. Biocompatibility analysis confirmed that the human umbilical vein endothelial cells (HUVECs) encapsulated within the three-dimensional (3D), conductive blended hydrogels were highly viable. Furthermore, we confirmed that the molecule in the conductive blended hydrogel was released by electrical stimuli-mediated structural deformation. Therefore, this conductive GelMA–collagen–AgNW blended hydrogel could be potentially used as a smart actuator for drug delivery applications. Full article
(This article belongs to the Special Issue The Diagnostics Based on Polymers)
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15 pages, 698 KiB  
Article
Formation and Evaluation of a Two-Phase Polymer System in Human Plasma as a Method for Extracellular Nanovesicle Isolation
by Maria Slyusarenko, Nadezhda Nikiforova, Elena Sidina, Inga Nazarova, Vladimir Egorov, Yuri Garmay, Anastasiia Merdalimova, Natalia Yevlampieva, Dmitry Gorin and Anastasia Malek
Polymers 2021, 13(3), 458; https://doi.org/10.3390/polym13030458 - 31 Jan 2021
Cited by 16 | Viewed by 4087
Abstract
The aim of the study was to explore the polyethylene glycol–dextran two-phase polymer system formed in human plasma to isolate the exosome-enriched fraction of plasma extracellular nanovesicles (ENVs). Systematic analysis was performed to determine the optimal combination of the polymer mixture parameters (molecular [...] Read more.
The aim of the study was to explore the polyethylene glycol–dextran two-phase polymer system formed in human plasma to isolate the exosome-enriched fraction of plasma extracellular nanovesicles (ENVs). Systematic analysis was performed to determine the optimal combination of the polymer mixture parameters (molecular mass and concentration) that resulted in phase separation. The separated phases were analyzed by nanoparticle tracking analysis and Raman spectroscopy. The isolated vesicles were characterized by atomic force microscopy and dot blotting. In conclusion, the protein and microRNA contents of the isolated ENVs were assayed by flow cytometry and by reverse transcription followed by quantitative polymerase chain reaction (RT-qPCR), respectively. The presented results revealed the applicability of a new method for plasma ENV isolation and further analysis with a diagnostic purpose. Full article
(This article belongs to the Special Issue The Diagnostics Based on Polymers)
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