Chikungunya Virus and Emerging Alphaviruses—Volume II

Dear Colleagues,

We recently unveiled a Viruses Special Issue entitled "Chikungunya Virus and Emerging Alphaviruses," which has garnered remarkable interest and received numerous submissions. Given the outstanding success of the previous Special Issue, we are excited to extend an invitation to our colleagues to participate in a second volume of this Special Issue. Chikungunya virus (CHIKV) is a resurging arthropod-borne virus that is prevalent in tropical regions. Belonging to the Alphavirus genus, it is transmitted to humans through the bites of Aedes spp. infected mosquitoes, which are commonly found in many populous urban areas. CHIKV exerts a profound impact on global public health, particularly in middle- and low-income countries where healthcare access is often limited. Chikungunya infection typically manifests with an abrupt onset of fever, frequently followed by severe joint pain. The joint pain induced by the Chikungunya virus is often an incapacitating symptom, persisting for a few days to several weeks or even months. Additionally, other atypical neurological manifestations have been documented, including meningo-encephalitis, meningoencephalo-myeloradiculitis, myeloradiculitis, myelitis, myeloneuropathy, Guillain-Barré syndrome, and more. In addition to CHIKV, other significant Alphaviruses including Mayaro, Ross River, and Venezuelan equine encephalitis, among others, can cause diseases in humans. Despite their significance, as of now, there are no available treatments or vaccines to effectively manage Alphavirus infections.

Despite notable scientific progress, exemplified by the development of cutting-edge mRNA vaccines, the emergence of new viruses and the resurgence of existing ones continue to present substantial challenges to the field. For this Special Issue, we enthusiastically invite the submission of original research articles, comprehensive review articles, and concise short communications. We encourage contributions that advance our comprehension of Alphaviruses. The following topics are of particular interest for this Special Issue:
- Alphaviruses epidemiology and virus surveillance (emergence and virus evolution);
- Advances in diagnostics, treatment and vaccines;
- Basic virology molecular aspects;
- Alphaviruses pathogenesis (including, but not limited to, host response and host factors affecting infection outcome, animal models of infection, host innate and adaptive immunity, and  virus immune response evasion);
- Measures for control and prevention.

Dr. Rafael Freitas de Oliveira França
Prof. Dr. Rodrigo Stabeli
Dr. Mylena R. Pereira
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Viruses is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• chikungunya virus
• innate immune response
• adaptive immune response
• epidemiology
• diagnosis
• prevention
• vaccine
• animal model
• pathogenesis
• viral evolution
• in vitro
• in vivo

• Chikungunya Virus and Emerging Alphaviruses in Viruses (17 articles)