Special Issue "Viruses and Telomeres"
A special issue of Viruses (ISSN 1999-4915).
Deadline for manuscript submissions: 15 May 2017
Viruses and telomeres share fundamental genetic and evolutionary properties. Telomeres are repetitive sequences at the ends of linear chromosomes of most organisms that are associated with a number of proteins. They counteract the loss of genetic material and can be maintained by a self-replication mechanism mediated by the telomerase complex. In many ways, the extension of telomeres resembles virus replication, and both share a clear evolutionary origin. It is therefore no surprise that many viruses have pirated components of telomeres and/or telomerase, including the telomeric repeats and telomerase RNA. Beyond that, viruses aquired the ability to modulate telomere maintenance and structure, including induction of telomerase activation or viral integration into host telomeres. In some cases, viruses and telomeres have a conflict of interest, with telomeres working to maintain host genome integrity and viruses seeking to be unleashed from these restraints. In other cases, viruses can take advantage of the telomere heterochromatin to establish latent or persistent infections in long-lived and dividing cells. How these interactions between viruses and host chromosomes are regulated and lead to pathogenesis is the subject of this volume.
Prof. Paul M. Lieberman
Prof. Benedikt B. Kaufer
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. Papers will be published continuously (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are refereed through a peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Viruses is an international peer-reviewed Open Access monthly journal published by MDPI.
- Human Herpesvirus 6
- Marek’s Disease Virus
- Epstein-Barr Virus