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Special Issue "Viruses and Telomeres"

A special issue of Viruses (ISSN 1999-4915).

Deadline for manuscript submissions: closed (15 May 2017)

Special Issue Editors

Guest Editor
Prof. Paul M. Lieberman

The Wistar Institute, Philadelphia, PA 19104, USA
Website | E-Mail
Interests: human gammaherpesvirus latency; and telomere chromatin regulation
Guest Editor
Prof. Benedikt B. Kaufer

Institut für Virologie, Freie Universität Berlin, Germany
Website | E-Mail
Interests: herpesvirus latency and integration into host telomeres

Special Issue Information

Dear Colleagues,

Viruses and telomeres share fundamental genetic and evolutionary properties.  Telomeres are repetitive sequences at the ends of linear chromosomes of most organisms that are associated with a number of proteins. They counteract the loss of genetic material and can be maintained by a self-replication mechanism mediated by the telomerase complex.  In many ways, the extension of telomeres resembles virus replication, and both share a clear evolutionary origin.  It is therefore no surprise that many viruses have pirated components of telomeres and/or telomerase, including the telomeric repeats and telomerase RNA. Beyond that, viruses aquired the ability to modulate telomere maintenance and structure, including induction of telomerase activation or viral integration into host telomeres.  In some cases, viruses and telomeres have a conflict of interest, with telomeres working to maintain host genome integrity and viruses seeking to be unleashed from these restraints.   In other cases, viruses can take advantage of the telomere heterochromatin to establish latent or persistent infections in long-lived and dividing cells.  How these interactions between viruses and host chromosomes are regulated and lead to pathogenesis is the subject of this volume. 

Prof. Paul M. Lieberman
Prof. Benedikt B. Kaufer
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Viruses is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1500 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

 

Keywords

  • telomere
  • virus
  • TERRA
  • telomerase
  • integration
  • Human Herpesvirus 6
  • Marek’s Disease Virus
  • Epstein-Barr Virus

 

Published Papers

This special issue is now open for submission.

Journal Contact

MDPI AG
Viruses Editorial Office
St. Alban-Anlage 66, 4052 Basel, Switzerland
E-Mail: 
Tel. +41 61 683 77 34
Fax: +41 61 302 89 18
Editorial Board
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