West Nile Virus
A special issue of Viruses (ISSN 1999-4915). This special issue belongs to the section "Animal Viruses".
Deadline for manuscript submissions: closed (30 November 2013) | Viewed by 169679
Special Issue Editors
Special Issue Information
Dear Colleagues,
West Nile virus (WNV) is an emerging mosquito-transmitted zoonotic pathogen that continues to spread throughout regions of the New World, Europe, Africa, and parts of the Middle East. Over the last decade, it has caused millions of human infections with outcomes ranging from sub-clinical illness, to a self-limiting febrile syndrome or lethal neuroinvasive disease. WNV poses a significant global public health risk and thus, has triggered intensive research into many areas related to WNV pathogenesis and disease. Among those targeted for exploration and discussion in this Special Edition are the epidemiology and clinical presentation of WNV disease, the virus-vector interface, vector ecology, WNV evolution and adaptation, the protective mammalian host immune response, mechanisms of virus immune evasion, and strategies for developing effective prophylaxis and treatments.
Prof. Dr. Michael S. Diamond
Dr. Ted C. Pierson
Guest Editors
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Keywords
- flavivirus
- pathogenesis
- encephalitis
- meningitis
- humoral immunity
- cellular immunity
- neutralization
- vaccine
- therapeutics
- mosquito
- neuron
- dendritic cells
- genetics
- neurotropism
- neuronal injury