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Medicina, Volume 54, Issue 1

2018 March - 10 articles

Cover Story: Angiogenesis, being one of the hallmarks of cancer, has long been the subject of intense study. Angiogenesis facilitates additional tumor growth which has made anti-angiogenic therapy an important field of research. Multiple anti-angiogenic agents have been developed targeting different pathways of angiogenesis, paving the way to future therapeutic cancer treatment. This article aims to delve into the prevailing winds of change in the exploitation of angiogenesis pathways as a strategy in the treatment of cancer. View Paper here.
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Articles (10)

  • Review
  • Open Access
63 Citations
8,321 Views
20 Pages

Angiogenesis: Managing the Culprits behind Tumorigenesis and Metastasis

  • Ashwaq Hamid Salem Yehya,
  • Muhammad Asif,
  • Sven Hans Petersen,
  • Ayappa V. Subramaniam,
  • Koji Kono,
  • Amin Malik Shah Abdul Majid and
  • Chern Ein Oon

Deregulated angiogenesis has been identified as a key contributor in a number of pathological conditions including cancer. It is a complex process, which involves highly regulated interaction of multiple signalling molecules. The pro-angiogenic signa...

  • Article
  • Open Access
7 Citations
3,617 Views
9 Pages

A Population-Based Surveillance Study on the Epidemiology of Hepatitis C in Estonia

  • Kairi Mansberg,
  • Karin Kull,
  • Riina Salupere,
  • Tiina Prükk,
  • Benno Margus,
  • Toomas Kariis,
  • Triin Remmel,
  • Külliki Suurmaa,
  • Kristi Ott and
  • Jelena Šmidt
  • + 1 author

Background and objective: The hepatitis C virus (HCV)-infected patients serve as a reservoir for transmission of the disease to others and are at risk of developing chronic hepatitis C, cirrhosis, and hepatocellular carcinoma. Although the epidemiolo...

  • Article
  • Open Access
4 Citations
3,901 Views
11 Pages

Salt Consumption in Latvian Population: A Pilot Study

  • Ilva Lazda,
  • Māris Goldmanis and
  • Inese Siksna

25 March 2018

Background and objective: High dietary sodium intake is associated with multiple health risks, and the average sodium intake in Latvia is higher than the World Health Organization has recommended. In Latvia, no study so far has combined self-reported...

  • Article
  • Open Access
5 Citations
3,868 Views
9 Pages

Eating Patterns and Food Choices of Latvian Infants during Their First Year of Life

  • Inga Sirina,
  • Ieva Strele,
  • Inese Siksna and
  • Dace Gardovska

Introduction: Pregnancy, infancy, and early childhood are periods of rapid growth and development. The role of nutrition is very important during these critical growth and development periods. The aim of the study was to investigate infant feeding pr...

  • Article
  • Open Access
43 Citations
7,484 Views
11 Pages

Background and objective: Amblyopia is the leading cause of visual impairment in children and adults and is very common during childhood. The aim of this study was to identify the prevalence and the risk factors of amblyopia in a pediatric population...

  • Article
  • Open Access
12 Citations
4,255 Views
8 Pages

Incidence and Mortality Patterns of Acute Myeloid Leukemia in Belgrade, Serbia (1999–2013)

  • Natasa Maksimovic,
  • Milica Zaric,
  • Tatjana Gazibara,
  • Goran Trajkovic,
  • Gorica Maric,
  • Dragan Miljus,
  • Nada Suvajdzic Vukovic,
  • Dragica Tomin,
  • Marijana Virijevic and
  • Tatjana Pekmezovic
  • + 1 author

Introduction: To assess incidence and mortality trends of acute myeloid leukemia (AML) in Belgrade (Serbia) in a 15-year period (from 1999 to 2013). Material and Methods: Data were obtained from the Cancer Registry of Serbia, Institute of Public Heal...

  • Article
  • Open Access
1 Citations
3,193 Views
8 Pages

Differences in Risk Factors and Prevalence of Vascular Calcification between Pre-Dialysis and Hemodialysis Balkan Nephropathy Patients

  • Nenad Petković,
  • Siniša Ristić,
  • Jelena Marinković,
  • Radmil Marić,
  • Marijana Kovačević and
  • Ljubica Djukanović

Aims: The aim of this study was to compare the risk factors and prevalence of vascular calcification (VC) in pre-dialysis and hemodialysis (HD) patients with Balkan endemic nephropathy (BEN) or other kidney diseases (non-BEN). Materials and Methods:...

  • Review
  • Open Access
37 Citations
6,949 Views
14 Pages

Point of Care Diagnostics for HIV in Resource Limited Settings: An Overview

  • Sello Lebohang Manoto,
  • Masixole Lugongolo,
  • Ureshnie Govender and
  • Patience Mthunzi-Kufa

Human immunodeficiency virus (HIV) is a global health problem. Early diagnosis, rapid antiretroviral therapy (ART) initiation and monitoring of viral load are the key strategies for effective HIV management. Many people in resource limited settings w...

  • Article
  • Open Access
17 Citations
4,785 Views
9 Pages

Background: Sufficient vaccination coverage among children depends on parents’ knowledge and attitudes towards immunization and their intention to have their children vaccinated. The objective of the study was to evaluate postpartum mothers’ knowledg...

  • Article
  • Open Access
35 Citations
4,753 Views
9 Pages

Effects of Silymarin-Loaded Nanoparticles on HT-29 Human Colon Cancer Cells

  • Maryam Mombeini,
  • Ghasem Saki,
  • Layasadat Khorsandi and
  • Neda Bavarsad

Background and objective: Previous studies have demonstrated the anti-cancer effects of silymarin (SLM). However, the low bioavailability of SLM has restricted its use. This study investigated the toxic effect of nanostructured SLM encapsulated in mi...

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Medicina - ISSN 1648-9144