A Case of Oncocytic Adrenal Cortical Neoplasm with Uncertain Malignant Potential Turned Out to Be Oncocytic Adrenal Cortical Carcinoma with Distant Metastasis: Could Pathology Do Better Initially?
Abstract
:1. Introduction
2. Case Report
3. Discussion
4. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Case 1 [4] | Case 2 [5] | Case 3 [6] | Case 4 [1] | Case 5 [1] | Case 6 [7] | Case 7 [8] | Current Case | |
---|---|---|---|---|---|---|---|---|
Age (years) | 74 | 54 | 54 | 53 | 41 | 45 | 45 | 42 |
Sex | F | M | M | F | F | F | M | F |
Laterality | L | R | R | L | L | R | L | L |
Metastatic site | ovary | Lung, rib, liver, contralateral adrenal gland | Lung, right hip | Not stated | Not stated | Femur, liver, lung, contralateral adrenal gland | lung | Scalp, lung |
Clinical presentation | Not stated | Not stated | Not stated | Virilization | Virilization | Abdominal pain | abdominal bloating | Abdominal pain |
Serum biochemistry | Not stated | ↑Cortisol | Not stated | ↑Androg | ↑Androg | Not stated | Not stated | Normal |
Size (cm); weight (g) | Not stated | Not stated | Not stated | 13; 670 | 28.5; 5720 | 11; 410 | 24; 6500 | 3.9; |
Mitotic count per 50HPF | Not stated | 14 | Not stated | 10 | 5 | >5 | 6 | <5 |
Atypical mitotic figures | Not stated | Absent | Not stated | Present | Present | Not stated | Present | Absent |
Venous invasion | Not stated | Present | Not stated | Present | Absent | Not stated | Absent | Absent |
Microscopic necrosis | Not stated | Present | Not stated | Present | Present | Not stated | Present | Present |
Capsular invasion | Not stated | Absent | Not stated | Present | Present | Absent | Absent | Absent |
Sinusoidal invasion | Not stated | Absent | Not stated | Present | Present | Not stated | Not stated | Present |
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Huang, C.-P.; Dai, M.-S.; Kao, C.-C.; Tsai, W.-C.; Yu, C.-P. A Case of Oncocytic Adrenal Cortical Neoplasm with Uncertain Malignant Potential Turned Out to Be Oncocytic Adrenal Cortical Carcinoma with Distant Metastasis: Could Pathology Do Better Initially? Medicina 2022, 58, 900. https://doi.org/10.3390/medicina58070900
Huang C-P, Dai M-S, Kao C-C, Tsai W-C, Yu C-P. A Case of Oncocytic Adrenal Cortical Neoplasm with Uncertain Malignant Potential Turned Out to Be Oncocytic Adrenal Cortical Carcinoma with Distant Metastasis: Could Pathology Do Better Initially? Medicina. 2022; 58(7):900. https://doi.org/10.3390/medicina58070900
Chicago/Turabian StyleHuang, Chien-Peng, Ming-Shen Dai, Chien-Chang Kao, Wen-Chiuan Tsai, and Cheng-Ping Yu. 2022. "A Case of Oncocytic Adrenal Cortical Neoplasm with Uncertain Malignant Potential Turned Out to Be Oncocytic Adrenal Cortical Carcinoma with Distant Metastasis: Could Pathology Do Better Initially?" Medicina 58, no. 7: 900. https://doi.org/10.3390/medicina58070900