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Open AccessReview
Anterior Segment Optical Coherence Tomography Angiography: A Review of Applications for the Cornea and Ocular Surface
by
Brian Juin Hsien Lee
Brian Juin Hsien Lee 1,
Kai Yuan Tey
Kai Yuan Tey 1,2,
Ezekiel Ze Ken Cheong
Ezekiel Ze Ken Cheong 3,
Qiu Ying Wong
Qiu Ying Wong 1,2,
Chloe Si Qi Chua
Chloe Si Qi Chua 1,2 and
Marcus Ang
Marcus Ang 1,2,3,*
1
Singapore National Eye Centre, Singapore 168751, Singapore
2
Singapore Eye Research Institute, Singapore 168751, Singapore
3
Ophthalmology and Visual Sciences Academic Clinical Program, Duke-NUS Medical School, Singapore 169857, Singapore
*
Author to whom correspondence should be addressed.
Medicina 2024, 60(10), 1597; https://doi.org/10.3390/medicina60101597 (registering DOI)
Submission received: 15 August 2024
/
Revised: 19 September 2024
/
Accepted: 26 September 2024
/
Published: 28 September 2024
Abstract
Dye-based angiography is the main imaging modality in evaluating the vasculature of the eye. Although most commonly used to assess retinal vasculature, it can also delineate normal and abnormal blood vessels in the anterior segment diseases—but is limited due to its invasive, time-consuming methods. Thus, anterior segment optical coherence tomography angiography (AS-OCTA) is a useful non-invasive modality capable of producing high-resolution images to evaluate the cornea and ocular surface vasculature. AS-OCTA has demonstrated the potential to detect and delineate blood vessels in the anterior segment with quality images comparable to dye-based angiography. AS-OCTA has a diverse range of applications for the cornea and ocular surface, such as objective assessment of corneal neovascularization and response to various treatments; diagnosis and evaluation of ocular surface squamous neoplasia; and evaluation of ocular surface disease including limbal stem cell deficiency and ischemia. Our review aims to summarize the new developments and clinical applications of AS-OCTA for the cornea and ocular surface.
Share and Cite
MDPI and ACS Style
Lee, B.J.H.; Tey, K.Y.; Cheong, E.Z.K.; Wong, Q.Y.; Chua, C.S.Q.; Ang, M.
Anterior Segment Optical Coherence Tomography Angiography: A Review of Applications for the Cornea and Ocular Surface. Medicina 2024, 60, 1597.
https://doi.org/10.3390/medicina60101597
AMA Style
Lee BJH, Tey KY, Cheong EZK, Wong QY, Chua CSQ, Ang M.
Anterior Segment Optical Coherence Tomography Angiography: A Review of Applications for the Cornea and Ocular Surface. Medicina. 2024; 60(10):1597.
https://doi.org/10.3390/medicina60101597
Chicago/Turabian Style
Lee, Brian Juin Hsien, Kai Yuan Tey, Ezekiel Ze Ken Cheong, Qiu Ying Wong, Chloe Si Qi Chua, and Marcus Ang.
2024. "Anterior Segment Optical Coherence Tomography Angiography: A Review of Applications for the Cornea and Ocular Surface" Medicina 60, no. 10: 1597.
https://doi.org/10.3390/medicina60101597
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